Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI021548-20
Application #
6680524
Study Section
Special Emphasis Panel (ZRG1-VACC (01))
Program Officer
Klein, David L
Project Start
1984-08-01
Project End
2007-10-31
Budget Start
2003-11-01
Budget End
2004-10-31
Support Year
20
Fiscal Year
2004
Total Cost
$423,217
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Walker, Melissa M; Novak, Lea; Widener, Rebecca et al. (2016) PcpA Promotes Higher Levels of Infection and Modulates Recruitment of Myeloid-Derived Suppressor Cells during Pneumococcal Pneumonia. J Immunol 196:2239-48
Hotomi, Muneki; Yuasa, Jun; Briles, David E et al. (2016) Pneumolysin plays a key role at the initial step of establishing pneumococcal nasal colonization. Folia Microbiol (Praha) 61:375-83
Dennis, Evida A; Coats, Mamie T; Griffin, Sarah E et al. (2015) The Effects of CFTR and Mucoid Phenotype on Susceptibility and Innate Immune Responses in a Mouse Model of Pneumococcal Lung Disease. PLoS One 10:e0140335
Kim, Ji-Yun; Paton, James C; Briles, David E et al. (2015) Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia. Oncotarget 6:44161-78
Schachern, Patricia A; Tsuprun, Vladimir; Ferrieri, Patricia et al. (2014) Pneumococcal PspA and PspC proteins: potential vaccine candidates for experimental otitis media. Int J Pediatr Otorhinolaryngol 78:1517-21
Zhao, H; Jung, J A; Briles, D E et al. (2013) Asthma and antibodies to pneumococcal virulence proteins. Infection 41:927-34
Genschmer, Kristopher R; Accavitti-Loper, Mary Ann; Briles, David E (2013) A modified surface killing assay (MSKA) as a functional in vitro assay for identifying protective antibodies against pneumococcal surface protein A (PspA). Vaccine 32:39-47
Ren, Bing; Li, Jie; Genschmer, Kristopher et al. (2012) The absence of PspA or presence of antibody to PspA facilitates the complement-dependent phagocytosis of pneumococci in vitro. Clin Vaccine Immunol 19:1574-82
Park, In Ho; Kim, Kyung-Hyo; Andrade, Ana Lucia et al. (2012) Nontypeable pneumococci can be divided into multiple cps types, including one type expressing the novel gene pspK. MBio 3:
Singh, Rajesh; Singh, Shailesh; Briles, David E et al. (2012) CCL5-independent helper T lymphocyte responses to immuno-dominant pneumococcal surface protein A epitopes. Vaccine 30:1181-90

Showing the most recent 10 out of 107 publications