Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI022001-13A1S1
Application #
2522799
Study Section
Virology Study Section (VR)
Project Start
1984-07-01
Project End
2002-03-31
Budget Start
1997-04-01
Budget End
1998-03-31
Support Year
13
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Louisiana State University Hsc Shreveport
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Shreveport
State
LA
Country
United States
Zip Code
71103
Shakya, Akhalesh K; O'Callaghan, Dennis J; Kim, Seong K (2017) Comparative Genomic Sequencing and Pathogenic Properties of Equine Herpesvirus 1 KyA and RacL11. Front Vet Sci 4:211
Charvat, Robert A; Zhang, Yunfei; O'Callaghan, Dennis J (2012) Deletion of the UL4 gene sequence of equine herpesvirus 1 precludes the generation of defective interfering particles. Virus Genes 45:295-303
Dai, Gan; Kim, Seongman; O'Callaghan, Dennis J et al. (2012) Development of a bacterial artificial chromosome (BAC) recombineering procedure using galK-untranslated region (UTR) for the mutation of diploid genes. J Virol Methods 182:18-26
Ahn, ByungChul; Zhang, Yunfei; Osterrieder, Nikolaus et al. (2011) Properties of an equine herpesvirus 1 mutant devoid of the internal inverted repeat sequence of the genomic short region. Virology 410:327-35
Kim, Seong K; Kim, Seongman; Dai, Gan et al. (2011) Identification of functional domains of the IR2 protein of equine herpesvirus 1 required for inhibition of viral gene expression and replication. Virology 417:430-42
Ahn, Byung Chul; Kim, Seongman; Zhang, Yunfei et al. (2011) The early UL3 gene of equine herpesvirus-1 encodes a tegument protein not essential for replication or virulence in the mouse. Virology 420:20-31
Charvat, Robert A; Breitenbach, Jonathan E; Ahn, ByungChul et al. (2011) The UL4 protein of equine herpesvirus 1 is not essential for replication or pathogenesis and inhibits gene expression controlled by viral and heterologous promoters. Virology 412:366-77
Ahn, Byung Chul; Zhang, Yunfei; O'Callaghan, Dennis J (2010) The equine herpesvirus-1 (EHV-1) IR3 transcript downregulates expression of the IE gene and the absence of IR3 gene expression alters EHV-1 biological properties and virulence. Virology 402:327-37
Breitenbach, Jonathan E; Ebner, Paul D; O'Callaghan, Dennis J (2009) The IR4 auxiliary regulatory protein expands the in vitro host range of equine herpesvirus 1 and is essential for pathogenesis in the murine model. Virology 383:188-94
Ebner, Paul D; Kim, Seong K; O'Callaghan, Dennis J (2008) Biological and genotypic properties of defective interfering particles of equine herpesvirus 1 that mediate persistent infection. Virology 381:98-105

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