Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI022444-11
Application #
2061818
Study Section
Special Emphasis Panel (ZRG5-TMP (01))
Project Start
1985-09-01
Project End
1996-12-31
Budget Start
1995-12-01
Budget End
1996-12-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Temple University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Boudko, D Y; Moroz, L L; Harvey, W R et al. (2001) Alkalinization by chloride/bicarbonate pathway in larval mosquito midgut. Proc Natl Acad Sci U S A 98:15354-9
Gruber, G; Wieczorek, H; Harvey, W R et al. (2001) Structure-function relationships of A-, F- and V-ATPases. J Exp Biol 204:2597-605
Boudko, D Y; Moroz, L L; Linser, P J et al. (2001) In situ analysis of pH gradients in mosquito larvae using non-invasive, self-referencing, pH-sensitive microelectrodes. J Exp Biol 204:691-9
Wieczorek, H; Grber, G; Harvey, W R et al. (2000) Structure and regulation of insect plasma membrane H(+)V-ATPase. J Exp Biol 203:127-35
Merzendorfer, H; Reineke, S; Zhao, X F et al. (2000) The multigene family of the tobacco hornworm V-ATPase: novel subunits a, C, D, H, and putative isoforms. Biochim Biophys Acta 1467:369-79
Gruber, G; Svergun, D I; Godovac-Zimmermann, J et al. (2000) Evidence for major structural changes in the Manduca sexta midgut V1 ATPase due to redox modulation. A small angle X-ray scattering study. J Biol Chem 275:30082-7
Svergun, D I; Becirevic, A; Schrempf, H et al. (2000) Solution structure and conformational changes of the Streptomyces chitin-binding protein (CHB1). Biochemistry 39:10677-83
Wieczorek, H; Gruber, G; Harvey, W R et al. (1999) The plasma membrane H+-V-ATPase from tobacco hornworm midgut. J Bioenerg Biomembr 31:67-74
Wieczorek, H; Brown, D; Grinstein, S et al. (1999) Animal plasma membrane energization by proton-motive V-ATPases. Bioessays 21:637-48
Zhuang, Z; Linser, P J; Harvey, W R (1999) Antibody to H(+) V-ATPase subunit E colocalizes with portasomes in alkaline larval midgut of a freshwater mosquito (Aedes aegypti). J Exp Biol 202:2449-60

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