Immunoregulatory T-Lymphocytes in Leprosy Skin Lesions

Modlin, Robert L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 7R01AI022553-07
• Application #: 3133795
• Study Section: Bacteriology and Mycology Subcommittee 2 (BM)
• Project Start: 1991-01-01
• Project End: 1993-06-30
• Budget Start: 1991-01-01
• Budget End: 1991-06-30
• Support Year: 7
• Fiscal Year: 1990

Institution

• Name: University of California Los Angeles
• Type: Schools of Medicine
• DUNS #: 119132785
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90095

Publications

Keegan, Caroline; Krutzik, Stephan; Schenk, Mirjam et al. (2018) Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. J Immunol 200:3244-3258

Madigan, Cressida A; Cambier, C J; Kelly-Scumpia, Kindra M et al. (2017) A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy. Cell 170:973-985.e10

Lopez, David; Montoya, Dennis; Ambrose, Michael et al. (2017) SaVanT: a web-based tool for the sample-level visualization of molecular signatures in gene expression profiles. BMC Genomics 18:824

Scumpia, Philip O; Botten, Giovanni A; Norman, Joshua S et al. (2017) Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense. PLoS Pathog 13:e1006496

Realegeno, Susan; Kelly-Scumpia, Kindra M; Dang, Angeline Tilly et al. (2016) S100A12 Is Part of the Antimicrobial Network against Mycobacterium leprae in Human Macrophages. PLoS Pathog 12:e1005705

Kibbie, Jon; Teles, Rosane M B; Wang, Zhiming et al. (2016) Jagged1 Instructs Macrophage Differentiation in Leprosy. PLoS Pathog 12:e1005808

Schenk, Mirjam; Mahapatra, Sebabrata; Le, Phuonganh et al. (2016) Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae. Infect Immun 84:2429-38

Rotcheewaphan, Suwatchareeporn; Belisle, John T; Webb, Kristofor J et al. (2016) Diguanylate cyclase activity of the Mycobacterium leprae T cell antigen ML1419c. Microbiology 162:1651-1661

Inkeles, Megan S; Teles, Rosane M B; Pouldar, Delila et al. (2016) Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy. JCI Insight 1:e88843

Busch, Martin; Herzmann, Christian; Kallert, Stephanie et al. (2016) Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis. Am J Respir Crit Care Med 194:345-55