Adhesins of Coagulase-Negative Staphylococci

Pier, Gerald B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 1R01AI023335-01A1
• Application #: 3135266
• Study Section: Bacteriology and Mycology Subcommittee 1 (BM)
• Project Start: 1987-05-01
• Project End: 1990-04-30
• Budget Start: 1987-05-01
• Budget End: 1988-04-30
• Support Year: 1
• Fiscal Year: 1987

Institution

• Name: Brigham and Women's Hospital
• DUNS #: 071723621
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02115

Publications

Huebner, J; Quaas, A; Krueger, W A et al. (2000) Prophylactic and therapeutic efficacy of antibodies to a capsular polysaccharide shared among vancomycin-sensitive and -resistant enterococci. Infect Immun 68:4631-6

Huebner, J; Wang, Y; Krueger, W A et al. (1999) Isolation and chemical characterization of a capsular polysaccharide antigen shared by clinical isolates of Enterococcus faecalis and vancomycin-resistant Enterococcus faecium. Infect Immun 67:1213-9

Wang, Y; Huebner, J; Tzianabos, A O et al. (1999) Structure of an antigenic teichoic acid shared by clinical isolates of Enterococcus faecalis and vancomycin-resistant Enterococcus faecium. Carbohydr Res 316:155-60

McKenney, D; Hubner, J; Muller, E et al. (1998) The ica locus of Staphylococcus epidermidis encodes production of the capsular polysaccharide/adhesin. Infect Immun 66:4711-20

Shiro, H; Muller, E; Takeda, S et al. (1995) Potentiation of Staphylococcus epidermidis catheter-related bacteremia by lipid infusions. J Infect Dis 171:220-4

Shiro, H; Meluleni, G; Groll, A et al. (1995) The pathogenic role of Staphylococcus epidermidis capsular polysaccharide/adhesin in a low-inoculum rabbit model of prosthetic valve endocarditis. Circulation 92:2715-22

Shiro, H; Muller, E; Gutierrez, N et al. (1994) Transposon mutants of Staphylococcus epidermidis deficient in elaboration of capsular polysaccharide/adhesin and slime are avirulent in a rabbit model of endocarditis. J Infect Dis 169:1042-9

Muller, E; Hubner, J; Gutierrez, N et al. (1993) Isolation and characterization of transposon mutants of Staphylococcus epidermidis deficient in capsular polysaccharide/adhesin and slime. Infect Immun 61:551-8

Muller, E; Takeda, S; Shiro, H et al. (1993) Occurrence of capsular polysaccharide/adhesin among clinical isolates of coagulase-negative staphylococci. J Infect Dis 168:1211-8

Muller, E; Takeda, S; Goldmann, D A et al. (1991) Blood proteins do not promote adherence of coagulase-negative staphylococci to biomaterials. Infect Immun 59:3323-6