Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI023538-10
Application #
2062256
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1986-06-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Crimmins, Gregory T; Mohammadi, Sina; Green, Erin R et al. (2012) Identification of MrtAB, an ABC transporter specifically required for Yersinia pseudotuberculosis to colonize the mesenteric lymph nodes. PLoS Pathog 8:e1002828
Isberg, R R; Barnes, P (2001) Subversion of integrins by enteropathogenic Yersinia. J Cell Sci 114:21-28
Alrutz, M A; Srivastava, A; Wong, K W et al. (2001) Efficient uptake of Yersinia pseudotuberculosis via integrin receptors involves a Rac1-Arp 2/3 pathway that bypasses N-WASP function. Mol Microbiol 42:689-703
Isberg, R R; Hamburger, Z; Dersch, P (2000) Signaling and invasin-promoted uptake via integrin receptors. Microbes Infect 2:793-801
Krukonis, E S; Isberg, R R (2000) Integrin beta1-chain residues involved in substrate recognition and specificity of binding to invasin. Cell Microbiol 2:219-30
Dersch, P; Isberg, R R (2000) An immunoglobulin superfamily-like domain unique to the Yersinia pseudotuberculosis invasin protein is required for stimulation of bacterial uptake via integrin receptors. Infect Immun 68:2930-8
Dersch, P; Isberg, R R (1999) A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association. EMBO J 18:1199-213
Alrutz, M A; Isberg, R R (1998) Involvement of focal adhesion kinase in invasin-mediated uptake. Proc Natl Acad Sci U S A 95:13658-63
Krukonis, E S; Dersch, P; Eble, J A et al. (1998) Differential effects of integrin alpha chain mutations on invasin and natural ligand interaction. J Biol Chem 273:31837-43
Krukonis, E S; Isberg, R R (1998) SWIM analysis allows rapid identification of residues involved in invasin-mediated bacterial uptake. Gene 211:109-16

Showing the most recent 10 out of 33 publications