Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI024157-02
Application #
3136908
Study Section
Immunobiology Study Section (IMB)
Project Start
1987-04-01
Project End
1990-03-31
Budget Start
1988-04-01
Budget End
1989-03-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Milam, Ashley A Viehmann; Bartleson, Juliet M; Donermeyer, David L et al. (2018) Tuning T Cell Signaling Sensitivity Alters the Behavior of CD4+ T Cells during an Immune Response. J Immunol 200:3429-3437
Viehmann Milam, Ashley A; Allen, Paul M (2017) The TCR Takes Some Immune Responsibility. Immunity 47:803-804
Ransdell, Joseph L; Dranoff, Edward; Lau, Brandon et al. (2017) Loss of Nav?4-Mediated Regulation of Sodium Currents in Adult Purkinje Neurons Disrupts Firing and Impairs Motor Coordination and Balance. Cell Rep 19:532-544
Hong, Jinsung; Persaud, Stephen P; Horvath, Stephen et al. (2015) Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells. J Immunol 195:3557-64
Rodriguez, Stephanie N; Jiang, Meizi; Bujo, Hideaki et al. (2015) Self-pMHCII complexes are variably expressed in the thymus and periphery independent of mRNA expression but dependent on the activation state of the APCs. Mol Immunol 63:428-36
Chou, Chun; Pinto, Amelia K; Curtis, Jonathan D et al. (2014) c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells. Nat Immunol 15:884-93
Ni, Peggy P; Wang, Yaming; Allen, Paul M (2014) Both positive and negative effects on immune responses by expression of a second class II MHC molecule. Mol Immunol 62:199-208
Lo, Wan-Lin; Solomon, Benjamin D; Donermeyer, David L et al. (2014) T cell immunodominance is dictated by the positively selecting self-peptide. Elife 3:e01457
KC, Wumesh; Satpathy, Ansuman T; Rapaport, Aaron S et al. (2014) L-Myc expression by dendritic cells is required for optimal T-cell priming. Nature 507:243-7
Klein, Ludger; Kyewski, Bruno; Allen, Paul M et al. (2014) Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see). Nat Rev Immunol 14:377-91

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