Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI024158-09
Application #
2062488
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1986-12-01
Project End
2001-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Utah
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Donius, Luke R; Weis, Janis J; Weis, John H (2014) Murine complement receptor 1 is required for germinal center B cell maintenance but not initiation. Immunobiology 219:440-9
Donius, Luke R; Orlando, Christopher M; Weis, Janis J et al. (2014) Generation of a novel Cr2 gene allele by homologous recombination that abrogates production of Cr2 but is sufficient for expression of Cr1. Immunobiology 219:53-63
Pioli, Peter D; Debnath, Irina; Weis, Janis J et al. (2014) Zfp318 regulates IgD expression by abrogating transcription termination within the Ighm/Ighd locus. J Immunol 193:2546-53
Pioli, Peter D; Weis, John H (2014) Snail transcription factors in hematopoietic cell development: a model of functional redundancy. Exp Hematol 42:425-30
Debnath, Irina; Roundy, Kirstin M; Pioli, Peter D et al. (2013) Bone marrow-induced Mef2c deficiency delays B-cell development and alters the expression of key B-cell regulatory proteins. Int Immunol 25:99-115
Pioli, Peter D; Dahlem, Timothy J; Weis, Janis J et al. (2013) Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency. PLoS One 8:e69216
Donius, Luke R; Handy, Jennifer M; Weis, Janis J et al. (2013) Optimal germinal center B cell activation and T-dependent antibody responses require expression of the mouse complement receptor Cr1. J Immunol 191:434-47
Dahlem, Timothy; Cho, Scott; Spangrude, Gerald J et al. (2012) Overexpression of Snai3 suppresses lymphoid- and enhances myeloid-cell differentiation. Eur J Immunol 42:1038-43
Bramwell, Kenneth K C; Ma, Ying; Weis, John H et al. (2012) High-throughput genotyping of advanced congenic lines by high resolution melting analysis for identification of Bbaa2, a QTL controlling Lyme arthritis. Biotechniques 52:183-90
Lochhead, Robert B; Sonderegger, F Lynn; Ma, Ying et al. (2012) Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue. J Immunol 189:2488-501

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