Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI024541-04
Application #
3137602
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1987-04-01
Project End
1992-03-31
Budget Start
1990-04-01
Budget End
1991-03-31
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Wistar Institute
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Weissler, Katherine A; Garcia, Victoria; Kropf, Elizabeth et al. (2015) Distinct modes of antigen presentation promote the formation, differentiation, and activity of foxp3+ regulatory T cells in vivo. J Immunol 194:3784-97
Weissler, Katherine A; Caton, Andrew J (2014) The role of T-cell receptor recognition of peptide:MHC complexes in the formation and activity of Foxp3? regulatory T cells. Immunol Rev 259:11-22
Perng, Olivia A; Aitken, Malinda; Rankin, Andrew L et al. (2014) The degree of CD4+ T cell autoreactivity determines cellular pathways underlying inflammatory arthritis. J Immunol 192:3043-56
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Simons, Donald M; Oh, Soyoung; Kropf, Elizabeth et al. (2013) Autoreactive Th1 cells activate monocytes to support regional Th17 responses in inflammatory arthritis. J Immunol 190:3134-41
Oh, Soyoung; Aitken, Malinda; Simons, Donald M et al. (2012) Requirement for diverse TCR specificities determines regulatory T cell activity in a mouse model of autoimmune arthritis. J Immunol 188:4171-80
Juchem, Kathryn W; Anderson, Britt E; Zhang, Cuiling et al. (2011) A repertoire-independent and cell-intrinsic defect in murine GVHD induction by effector memory T cells. Blood 118:6209-19
Simons, Donald M; Picca, Cristina Cozzo; Oh, Soyoung et al. (2010) How specificity for self-peptides shapes the development and function of regulatory T cells. J Leukoc Biol 88:1099-107
Hondowicz, Brian D; Batheja, Amrita O; Metzgar, Michele H et al. (2010) ICOS expression by effector T cells influences the ability of regulatory T cells to inhibit anti-chromatin B cell responses in recipient mice. J Autoimmun 34:460-8
Oh, Soyoung; Rankin, Andrew L; Caton, Andrew J (2010) CD4+CD25+ regulatory T cells in autoimmune arthritis. Immunol Rev 233:97-111

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