Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI024838-10
Application #
2062769
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1986-09-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
von Löhneysen, Katharina; Noack, Deborah; Wood, Malcolm R et al. (2010) Structural insights into Nox4 and Nox2: motifs involved in function and cellular localization. Mol Cell Biol 30:961-75
Luxen, Sylvia; Noack, Deborah; Frausto, Monika et al. (2009) Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells. J Cell Sci 122:1238-47
Lehmann, Mandy; Noack, Deborah; Wood, Malcolm et al. (2009) Lung epithelial injury by B. anthracis lethal toxin is caused by MKK-dependent loss of cytoskeletal integrity. PLoS One 4:e4755
von Lohneysen, Katharina; Noack, Deborah; Jesaitis, Algirdas J et al. (2008) Mutational analysis reveals distinct features of the Nox4-p22 phox complex. J Biol Chem 283:35273-82
Pacquelet, Sandrine; Lehmann, Mandy; Luxen, Sylvia et al. (2008) Inhibitory action of NoxA1 on dual oxidase activity in airway cells. J Biol Chem 283:24649-58
Maroto, B; Ye, M B; von Lohneysen, K et al. (2008) P21-activated kinase is required for mitotic progression and regulates Plk1. Oncogene 27:4900-8
Luxen, Sylvia; Belinsky, Steven A; Knaus, Ulla G (2008) Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer. Cancer Res 68:1037-45
Zhu, Yanmin; Marchal, Christophe C; Casbon, Amy-Jo et al. (2006) Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity. J Biol Chem 281:30336-46
Zhu, Hao; Larade, Kevin; Jackson, Timothy A et al. (2004) NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum. J Biol Chem 279:30316-25
Heyworth, Paul G; Cross, Andrew R; Curnutte, John T (2003) Chronic granulomatous disease. Curr Opin Immunol 15:578-84

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