Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI025231-17
Application #
6770169
Study Section
Experimental Virology Study Section (EVR)
Program Officer
Park, Eun-Chung
Project Start
1988-02-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
17
Fiscal Year
2004
Total Cost
$527,465
Indirect Cost
Name
University of Colorado Denver
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Hirai, Asuka; Ohtsuka, Nobuhisa; Ikeda, Toshio et al. (2010) Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b. J Virol 84:6654-66
Miura, Tanya A; Holmes, Kathryn V (2009) Host-pathogen interactions during coronavirus infection of primary alveolar epithelial cells. J Leukoc Biol 86:1145-51
Miura, Tanya A; Wang, Jieru; Mason, Robert J et al. (2006) Rat coronavirus infection of primary rat alveolar epithelial cells. Adv Exp Med Biol 581:351-6
Thackray, Larissa B; Turner, Brian C; Holmes, Kathryn V (2005) Substitutions of conserved amino acids in the receptor-binding domain of the spike glycoprotein affect utilization of murine CEACAM1a by the murine coronavirus MHV-A59. Virology 334:98-110
Jeffers, Scott A; Tusell, Sonia M; Gillim-Ross, Laura et al. (2004) CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus. Proc Natl Acad Sci U S A 101:15748-53
Schickli, Jeanne H; Thackray, Larissa B; Sawicki, Stanley G et al. (2004) The N-terminal region of the murine coronavirus spike glycoprotein is associated with the extended host range of viruses from persistently infected murine cells. J Virol 78:9073-83
Tripet, Brian; Howard, Megan W; Jobling, Michael et al. (2004) Structural characterization of the SARS-coronavirus spike S fusion protein core. J Biol Chem 279:20836-49
Turner, Brian C; Hemmila, Erin M; Beauchemin, Nicole et al. (2004) Receptor-dependent coronavirus infection of dendritic cells. J Virol 78:5486-90
Thackray, Larissa B; Holmes, Kathryn V (2004) Amino acid substitutions and an insertion in the spike glycoprotein extend the host range of the murine coronavirus MHV-A59. Virology 324:510-24
Godfraind, C; Havaux, N; Holmes, K V et al. (1997) Role of virus receptor-bearing endothelial cells of the blood-brain barrier in preventing the spread of mouse hepatitis virus-A59 into the central nervous system. J Neurovirol 3:428-34