|
Rawal, Ravindra K; Singh, Uma S; Chavre, Satish N et al. (2013) 2'-Fluoro-6'-methylene-carbocyclic adenosine phosphoramidate (FMCAP) prodrug: in vitro anti-HBV activity against the lamivudine-entecavir resistant triple mutant and its mechanism of action. Bioorg Med Chem Lett 23:503-6
|
|
Wang, Jianing; Singh, Uma S; Rawal, Ravindra K et al. (2011) Antiviral activity of novel 2'-fluoro-6'-methylene-carbocyclic adenosine against wild-type and drug-resistant hepatitis B virus mutants. Bioorg Med Chem Lett 21:6328-31
|
|
Gadthula, Srinivas; Rawal, Ravindra K; Sharon, Ashoke et al. (2011) Synthesis and antiviral activity of cyclopropyl-spirocarbocyclic adenosine, (4R,5S,6R,7R)-4-(6-amino-9H-purin-9-yl)-7-(hydroxymethyl)spiro[2.4]heptane-5,6-diol against hepatitis C virus. Bioorg Med Chem Lett 21:3982-5
|
|
Friedman, Julia; Cho, Won-Kyung; Chu, Chung K et al. (2011) Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2. J Virol 85:9078-89
|
|
Sharon, Ashoke; Chu, Chung K (2008) Understanding the molecular basis of HBV drug resistance by molecular modeling. Antiviral Res 80:339-53
|
|
Liang, Yuzeng; Narayanasamy, Janarthanan; Schinazi, Raymond F et al. (2006) Phosphoramidate and phosphate prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine: synthesis, anti-HIV activity and stability studies. Bioorg Med Chem 14:2178-89
|
|
Liang, Yuzeng; Narayanasamy, Janarthanan; Rapp, Kim L et al. (2006) PAMAM dendrimers and branched polyethyleneglycol (nanoparticles) prodrugs of (-)-beta-D-(2R, 4R)-dioxolane-thymine (DOT) and their anti-HIV activity. Antivir Chem Chemother 17:321-9
|
|
Shi, Junxing; Du, Jinfa; Ma, Tianwei et al. (2005) Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides. Nucleosides Nucleotides Nucleic Acids 24:875-9
|
|
Ray, Adrian S; Hernandez-Santiago, Brenda I; Mathew, Judy S et al. (2005) Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine. Antimicrob Agents Chemother 49:1994-2001
|
|
Wang, Jianing; Jin, Yunho; Rapp, Kimberly L et al. (2005) Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides. J Med Chem 48:3736-48
|
Showing the most recent 10 out of 88 publications
