Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI026363-04S1
Application #
3140147
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1988-04-01
Project End
1993-03-31
Budget Start
1991-09-01
Budget End
1992-03-31
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
He, Xiao; Woodford-Thomas, Terry A; Johnson, Kenneth G et al. (2002) Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling. Eur J Immunol 32:2578-87
Kung, C; Okumura, M; Seavitt, J R et al. (1999) CD45-associated protein is not essential for the regulation of antigen receptor-mediated signal transduction. Eur J Immunol 29:3951-5
Morafo, V; Rath, S; Thomas, M L et al. (1999) Induction of a germinal center phenotype in B cells in vitro by a Th2 cell line. Cell Immunol 198:77-86
Kung, C; Thomas, M L (1999) Genomic organization and chromosomal localization of mouse coronin-1. Mamm Genome 10:523-5
Okumura, M; Kung, C; Wong, S et al. (1998) Definition of family of coronin-related proteins conserved between humans and mice: close genetic linkage between coronin-2 and CD45-associated protein. DNA Cell Biol 17:779-87
Ulyanova, T; Blasioli, J; Thomas, M L (1997) Regulation of cell signaling by the protein tyrosine phosphatases, CD45 and SHP-1. Immunol Res 16:101-13
Cahir McFarland, E D; Pingel, J; Thomas, M L (1997) Definition of amino acids sufficient for plasma membrane association of CD45 and CD45-associated protein. Biochemistry 36:7169-75
Kung, C; Thomas, M L (1997) Recent advances in lymphocyte signaling and regulation. Front Biosci 2:d207-21
Okumura, M; Matthews, R J; Robb, B et al. (1996) Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains. J Immunol 157:1569-75
Cahir McFarland, E D; Thomas, M L (1995) CD45 protein-tyrosine phosphatase associates with the WW domain-containing protein, CD45AP, through the transmembrane region. J Biol Chem 270:28103-7

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