Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI026847-09
Application #
2063587
Study Section
Experimental Immunology Study Section (EI)
Project Start
1988-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Sciammas, R; Bluestone, J A (1998) HSV-1 glycoprotein I-reactive TCR gamma delta cells directly recognize the peptide backbone in a conformationally dependent manner. J Immunol 161:5187-92
Sperling, A I; Decker, D C; DiPaolo, R J et al. (1997) Selective expansion of Vgamma2-Vdelta7 TCR gammadelta cells in C57BL/6 mice is postnatal and extrathymic. J Immunol 159:86-91
Sciammas, R; Kodukula, P; Tang, Q et al. (1997) T cell receptor-gamma/delta cells protect mice from herpes simplex virus type 1-induced lethal encephalitis. J Exp Med 185:1969-75
Khattri, R; Sperling, A I; Qian, D et al. (1996) TCR-gamma delta cells in CD3 zeta-deficient mice contain Fc epsilon RI gamma in the receptor complex but are specifically unresponsive to antigen. J Immunol 157:2320-7
Sandor, M; Sperling, A I; Cook, G A et al. (1995) Two waves of gamma delta T cells expressing different V delta genes are recruited into schistosome-induced liver granulomas. J Immunol 155:275-84
Sciammas, R; Johnson, R M; Sperling, A I et al. (1994) Unique antigen recognition by a herpesvirus-specific TCR-gamma delta cell. J Immunol 152:5392-7
Tatsumi, Y; Deluca, D; Cron, R Q et al. (1994) Differential effects of T cell receptor ligation of TCR gamma delta thymocyte development in fetal thymic organ culture. Thymus 23:131-53
Barrett, T A; Tatsumi, Y; Bluestone, J A (1993) Tolerance of T cell receptor gamma/delta cells in the intestine. J Exp Med 177:1755-62
Sperling, A I; Linsley, P S; Barrett, T A et al. (1993) CD28-mediated costimulation is necessary for the activation of T cell receptor-gamma delta+ T lymphocytes. J Immunol 151:6043-50
Peterman, G M; Spencer, C; Sperling, A I et al. (1993) Role of gamma delta T cells in murine collagen-induced arthritis. J Immunol 151:6546-58

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