Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI027161-12
Application #
6534009
Study Section
Virology Study Section (VR)
Program Officer
Meegan, James M
Project Start
1989-02-01
Project End
2004-06-30
Budget Start
2002-09-01
Budget End
2003-06-30
Support Year
12
Fiscal Year
2002
Total Cost
$257,429
Indirect Cost
Name
Donald Danforth Plant Science Center
Department
Type
DUNS #
City
St. Louis
State
MO
Country
United States
Zip Code
63132
Bendahmane, Mohammed; Chen, Iju; Asurmendi, Sebastian et al. (2007) Coat protein-mediated resistance to TMV infection of Nicotiana tabacum involves multiple modes of interference by coat protein. Virology 366:107-16
Asurmendi, S; Berg, R H; Smith, T J et al. (2007) Aggregation of TMV CP plays a role in CP functions and in coat-protein-mediated resistance. Virology 366:98-106
Bazzini, A A; Asurmendi, S; Hopp, H E et al. (2006) Tobacco mosaic virus (TMV) and potato virus X (PVX) coat proteins confer heterologous interference to PVX and TMV infection, respectively. J Gen Virol 87:1005-12
Voloudakis, A E; Aleman-Verdaguer, M-E; Padgett, H S et al. (2005) Characterization of resistance in transgenic Nicotiana benthamiana encoding N-terminal deletion and assembly mutants of the tobacco etch potyvirus coat protein. Arch Virol 150:2567-82
Voloudakis, A E; Malpica, C A; Aleman-Verdaguer, M-E et al. (2004) Structural characterization of Tobacco etch virus coat protein mutants. Arch Virol 149:699-712
Asurmendi, S; Berg, R H; Koo, J C et al. (2004) Coat protein regulates formation of replication complexes during tobacco mosaic virus infection. Proc Natl Acad Sci U S A 101:1415-20
Koo, Ja Choon; Asurmendi, Sebastian; Bick, Jennifer et al. (2004) Ecdysone agonist-inducible expression of a coat protein gene from tobacco mosaic virus confers viral resistance in transgenic Arabidopsis. Plant J 37:439-48
Bendahmane, Mohammed; Szecsi, Judit; Chen, Iju et al. (2002) Characterization of mutant tobacco mosaic virus coat protein that interferes with virus cell-to-cell movement. Proc Natl Acad Sci U S A 99:3645-50
Staczek, J; Bendahmane, M; Gilleland, L B et al. (2000) Immunization with a chimeric tobacco mosaic virus containing an epitope of outer membrane protein F of Pseudomonas aeruginosa provides protection against challenge with P. aeruginosa. Vaccine 18:2266-74
Opalka, N; Tihova, M; Brugidou, C et al. (2000) Structure of native and expanded sobemoviruses by electron cryo-microscopy and image reconstruction. J Mol Biol 303:197-211

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