Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI027863-14
Application #
6631764
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Savarese, Barbara M
Project Start
1990-01-01
Project End
2006-04-30
Budget Start
2003-05-01
Budget End
2004-04-30
Support Year
14
Fiscal Year
2003
Total Cost
$313,200
Indirect Cost

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Gangaiah, Dharanesh; Zhang, Xinjun; Baker, Beth et al. (2016) Haemophilus ducreyi Seeks Alternative Carbon Sources and Adapts to Nutrient Stress and Anaerobiosis during Experimental Infection of Human Volunteers. Infect Immun 84:1514-1525
Singer, Martin; Li, Wei; Morré, Servaas A et al. (2016) Host Polymorphisms in TLR9 and IL10 Are Associated With the Outcomes of Experimental Haemophilus ducreyi Infection in Human Volunteers. J Infect Dis 214:489-95
van Rensburg, Julia J; Lin, Huaiying; Gao, Xiang et al. (2015) The Human Skin Microbiome Associates with the Outcome of and Is Influenced by Bacterial Infection. MBio 6:e01315-15
Gangaiah, Dharanesh; Webb, Kristen M; Humphreys, Tricia L et al. (2015) Haemophilus ducreyi Cutaneous Ulcer Strains Are Nearly Identical to Class I Genital Ulcer Strains. PLoS Negl Trop Dis 9:e0003918
Holley, Concerta L; Zhang, Xinjun; Fortney, Kate R et al. (2015) DksA and (p)ppGpp have unique and overlapping contributions to Haemophilus ducreyi pathogenesis in humans. Infect Immun 83:3281-92
Trombley, Michael P; Post, Deborah M B; Rinker, Sherri D et al. (2015) Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro. PLoS One 10:e0124373
Holley, Concerta; Gangaiah, Dharanesh; Li, Wei et al. (2014) A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes. Infect Immun 82:3492-502
Gangaiah, Dharanesh; Zhang, Xinjun; Baker, Beth et al. (2014) Haemophilus ducreyi RpoE and CpxRA appear to play distinct yet complementary roles in regulation of envelope-related functions. J Bacteriol 196:4012-25
Zhang, Xinjun; Gangaiah, Dharanesh; Munson Jr, Robert S et al. (2014) Correcting imbalanced reads coverage in bacterial transcriptome sequencing with extreme deep coverage. Int J Comput Biol Drug Des 7:195-213
Gangaiah, Dharanesh; Labandeira-Rey, Maria; Zhang, Xinjun et al. (2014) Haemophilus ducreyi Hfq contributes to virulence gene regulation as cells enter stationary phase. MBio 5:e01081-13

Showing the most recent 10 out of 19 publications