Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI029478-06S1
Application #
2065017
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1991-01-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
605799469
City
Newark
State
NJ
Country
United States
Zip Code
07107
Liu, Wenzhe; Das, Anish; Morales, Rachel et al. (2012) Chromatin immunoprecipitation and microarray analysis reveal that TFIIB occupies the SL RNA gene promoter region in Trypanosoma brucei chromosomes. Mol Biochem Parasitol 186:139-42
Ibrahim, B Syed; Kanneganti, Nalini; Rieckhof, Gabrielle E et al. (2009) Structure of the C-terminal domain of transcription factor IIB from Trypanosoma brucei. Proc Natl Acad Sci U S A 106:13242-7
Das, Anish; Bellofatto, Vivian (2009) The non-canonical CTD of RNAP-II is essential for productive RNA synthesis in Trypanosoma brucei. PLoS One 4:e6959
Bellofatto, Vivian; Palenchar, Jennifer B (2008) RNA interference as a genetic tool in trypanosomes. Methods Mol Biol 442:83-94
Das, Anish; Banday, Mahrukh; Bellofatto, Vivian (2008) RNA polymerase transcription machinery in trypanosomes. Eukaryot Cell 7:429-34
Bellofatto, Vivian (2007) Pyrimidine transport activities in trypanosomes. Trends Parasitol 23:187-9;discussion 190
Palenchar, Jennifer B; Liu, Wenzhe; Palenchar, Peter M et al. (2006) A divergent transcription factor TFIIB in trypanosomes is required for RNA polymerase II-dependent spliced leader RNA transcription and cell viability. Eukaryot Cell 5:293-300
Das, Anish; Li, Hong; Liu, Tong et al. (2006) Biochemical characterization of Trypanosoma brucei RNA polymerase II. Mol Biochem Parasitol 150:201-10
Das, Anish; Zhang, Qing; Palenchar, Jennifer B et al. (2005) Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression. Mol Cell Biol 25:7314-22
Gilinger, Gwen; Luo, Hua; Bellofatto, Vivian (2004) In vivo transcription analysis utilizing chromatin immunoprecipation reveals a role for trypanosome transcription factor PBP-1 in RNA polymerase III-dependent transcription. Mol Biochem Parasitol 134:169-73

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