Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029672-07
Application #
2065139
Study Section
Immunobiology Study Section (IMB)
Project Start
1992-06-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Feeney, Ann J (2011) Epigenetic regulation of antigen receptor gene rearrangement. Curr Opin Immunol 23:171-7
Degner, Stephanie C; Verma-Gaur, Jiyoti; Wong, Timothy P et al. (2011) CCCTC-binding factor (CTCF) and cohesin influence the genomic architecture of the Igh locus and antisense transcription in pro-B cells. Proc Natl Acad Sci U S A 108:9566-71
Degner-Leisso, Stephanie C; Feeney, Ann J (2010) Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes. Semin Immunol 22:346-52
Feeney, Ann (2010) Epigenetic regulation of V(D)J recombination. Semin Immunol 22:311-2
Lukin, Kara; Fields, Scott; Lopez, Desiree et al. (2010) Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression. Proc Natl Acad Sci U S A 107:7869-74
Feeney, Ann J (2009) Genetic and epigenetic control of V gene rearrangement frequency. Adv Exp Med Biol 650:73-81
Degner, Stephanie C; Wong, Timothy P; Jankevicius, Gytis et al. (2009) Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development. J Immunol 182:44-8
Xu, Cheng-Ran; Feeney, Ann J (2009) The epigenetic profile of Ig genes is dynamically regulated during B cell differentiation and is modulated by pre-B cell receptor signaling. J Immunol 182:1362-9
Carey, John B; Moffatt-Blue, Chantelle S; Watson, Lisa C et al. (2008) Repertoire-based selection into the marginal zone compartment during B cell development. J Exp Med 205:2043-52
Watson, Lisa C; Moffatt-Blue, Chantelle S; McDonald, R Zachary et al. (2006) Paucity of V-D-D-J rearrangements and VH replacement events in lupus prone and nonautoimmune TdT-/- and TdT+/+ mice. J Immunol 177:1120-8

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