Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI030479-05
Application #
2065635
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1991-02-01
Project End
1995-08-31
Budget Start
1995-02-01
Budget End
1995-08-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Dalebroux, Zachary D; Edrozo, Mauna B; Pfuetzner, Richard A et al. (2015) Delivery of cardiolipins to the Salmonella outer membrane is necessary for survival within host tissues and virulence. Cell Host Microbe 17:441-51
Hicks, Kevin G; Delbecq, Scott P; Sancho-Vaello, Enea et al. (2015) Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence. Elife 4:e06792
Matamouros, Susana; Hager, Kyle R; Miller, Samuel I (2015) HAMP Domain Rotation and Tilting Movements Associated with Signal Transduction in the PhoQ Sensor Kinase. MBio 6:e00616-15
LaRock, Doris L; Chaudhary, Anu; Miller, Samuel I (2015) Salmonellae interactions with host processes. Nat Rev Microbiol 13:191-205
Matamouros, Susana; Miller, Samuel I (2015) S. Typhimurium strategies to resist killing by cationic antimicrobial peptides. Biochim Biophys Acta 1848:3021-5
Thaipisuttikul, Iyarit; Hittle, Lauren E; Chandra, Ramesh et al. (2014) A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis-specific lipid A. Mol Microbiol 91:158-74
Dalebroux, Zachary D; Matamouros, Susana; Whittington, Dale et al. (2014) PhoPQ regulates acidic glycerophospholipid content of the Salmonella Typhimurium outer membrane. Proc Natl Acad Sci U S A 111:1963-8
Dalebroux, Zachary D; Miller, Samuel I (2014) Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity. Curr Opin Microbiol 17:106-13
Hajjar, Adeline M; Ernst, Robert K; Fortuno 3rd, Edgardo S et al. (2012) Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica. PLoS Pathog 8:e1002963
Pultz, Ingrid Swanson; Christen, Matthias; Kulasekara, Hemantha Don et al. (2012) The response threshold of Salmonella PilZ domain proteins is determined by their binding affinities for c-di-GMP. Mol Microbiol 86:1424-40

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