Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI030581-07
Application #
2065743
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1991-07-01
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
Quinn, Colleen A; Rollock, David; Vrana, Scott R (2014) A test of Spielberger's state-trait theory of anger with adolescents: five hypotheses. Emotion 14:74-84
Benitez, Andrea Caballero; Dai, Zhenpeng; Mann, Henning H et al. (2011) Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells. Proc Natl Acad Sci U S A 108:4081-6
Hanaoka, Nobuyoshi; Jabri, Bana; Dai, Zhenpeng et al. (2010) NKG2D initiates caspase-mediated CD3zeta degradation and lymphocyte receptor impairments associated with human cancer and autoimmune disease. J Immunol 185:5732-42
Dai, Zhenpeng; Turtle, Cameron J; Booth, Garrett C et al. (2009) Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J Exp Med 206:793-805
Venkataraman, Gopalakrishnan M; Suciu, Dominic; Groh, Veronika et al. (2007) Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D. J Immunol 178:961-9
Azimi, Nazli; Jacobson, Steven; Tanaka, Yuetsu et al. (2006) Immunostimulation by induced expression of NKG2D and its MIC ligands in HTLV-1-associated neurologic disease. Immunogenetics 58:252-8
Groh, Veronika; Smythe, Kimberly; Dai, Zhenpeng et al. (2006) Fas-ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity. Nat Immunol 7:755-62
Gonzalez, S; Groh, V; Spies, T (2006) Immunobiology of human NKG2D and its ligands. Curr Top Microbiol Immunol 298:121-38
Groh, Veronika; Li, Yongqing Q; Cioca, Daniel et al. (2005) Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells. Proc Natl Acad Sci U S A 102:6461-6
Somersalo, Kristina; Anikeeva, Nadja; Sims, Tasha N et al. (2004) Cytotoxic T lymphocytes form an antigen-independent ring junction. J Clin Invest 113:49-57

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