Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI031168-05
Application #
2066185
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1991-04-01
Project End
1996-12-31
Budget Start
1995-04-01
Budget End
1996-12-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Stanford University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Robinson, James; Guethlein, Lisbeth A; Cereb, Nezih et al. (2017) Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles. PLoS Genet 13:e1006862
Wroblewski, Emily E; Guethlein, Lisbeth A; Norman, Paul J et al. (2017) Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B. J Immunol 198:3480-3493
Guethlein, Lisbeth A; Norman, Paul J; Heijmans, Corinne M C et al. (2017) Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes. J Immunol 198:3157-3169
de Groot, Natasja G; Heijmans, Corrine M C; van der Wiel, Marit K H et al. (2016) Complex MHC Class I Gene Transcription Profiles and Their Functional Impact in Orangutans. J Immunol 196:750-8
Abi-Rached, Laurent; Guethlein, Lisbeth A; Norman, Paul J et al. (2015) Chimpanzee susceptibility to hepatitis C virus infection correlates with presence of Pt-KIR3DS2 and Pt-KIR2DL9: paired activating and inhibitory natural killer cell receptors. Immunogenetics 67:625-8
Wroblewski, Emily E; Norman, Paul J; Guethlein, Lisbeth A et al. (2015) Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz. PLoS Biol 13:e1002144
Goyos, Ana; Guethlein, Lisbeth A; Horowitz, Amir et al. (2015) A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule. J Immunol 195:3725-36
Guethlein, Lisbeth A; Norman, Paul J; Hilton, Hugo G et al. (2015) Co-evolution of MHC class I and variable NK cell receptors in placental mammals. Immunol Rev 267:259-82
Parham, Peter; Moffett, Ashley (2013) Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution. Nat Rev Immunol 13:133-44
Parham, P; Norman, P J; Abi-Rached, L et al. (2012) Review: Immunogenetics of human placentation. Placenta 33 Suppl:S71-80

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