Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI031563-04A2
Application #
2066547
Study Section
Experimental Virology Study Section (EVR)
Project Start
1991-08-01
Project End
2001-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199

  Publications

Kim, Arthur Y; Kuntzen, Thomas; Timm, Joerg et al. (2011) Spontaneous control of HCV is associated with expression of HLA-B 57 and preservation of targeted epitopes. Gastroenterology 140:686-696.e1
Kasprowicz, Victoria; Ward, Scott M; Turner, Alison et al. (2008) Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus. J Clin Invest 118:1143-53
Kasprowicz, Victoria; Schulze Zur Wiesch, Julian; Kuntzen, Thomas et al. (2008) High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome. J Virol 82:3154-60
Schulze Zur Wiesch, Julian; Lauer, Georg M; Timm, Joerg et al. (2007) Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection. Blood 110:1559-69
Timm, J; Neukamm, M; Kuntzen, T et al. (2007) Characterization of full-length hepatitis C virus genotype 4 sequences. J Viral Hepat 14:330-7
McGovern, Barbara H; Wurcel, Alysse; Kim, Arthur Y et al. (2006) Acute hepatitis C virus infection in incarcerated injection drug users. Clin Infect Dis 42:1663-70
Kim, Arthur Y; Schulze zur Wiesch, Julian; Kuntzen, Thomas et al. (2006) Impaired hepatitis C virus-specific T cell responses and recurrent hepatitis C virus in HIV coinfection. PLoS Med 3:e492
Schulze zur Wiesch, Julian; Lauer, Georg M; Day, Cheryl L et al. (2005) Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes. J Immunol 175:3603-13
Lauer, Georg M; Lucas, Michaela; Timm, Joerg et al. (2005) Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy. J Virol 79:12979-88
Timm, Joerg; Lauer, Georg M; Kavanagh, Daniel G et al. (2004) CD8 epitope escape and reversion in acute HCV infection. J Exp Med 200:1593-604

Showing the most recent 10 out of 18 publications