Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI031951-05
Application #
2066879
Study Section
Special Emphasis Panel (ZRG5-TMP (01))
Project Start
1992-02-01
Project End
2000-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Arizona
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Isoe, Jun; Stover, Weston; Miesfeld, R Barrett et al. (2013) COPI-mediated blood meal digestion in vector mosquitoes is independent of midgut ARF-GEF and ARF-GAP regulatory activities. Insect Biochem Mol Biol 43:732-9
Mack, Daniel J; Isoe, Jun; Miesfeld, Roger L et al. (2012) Distinct biological effects of golgicide a derivatives on larval and adult mosquitoes. Bioorg Med Chem Lett 22:5177-81
Alabaster, Amy; Isoe, Jun; Zhou, Guoli et al. (2011) Deficiencies in acetyl-CoA carboxylase and fatty acid synthase 1 differentially affect eggshell formation and blood meal digestion in Aedes aegypti. Insect Biochem Mol Biol 41:946-55
Isoe, Jun; Collins, Jennifer; Badgandi, Hemant et al. (2011) Defects in coatomer protein I (COPI) transport cause blood feeding-induced mortality in Yellow Fever mosquitoes. Proc Natl Acad Sci U S A 108:E211-7
Zhou, Guoli; Isoe, Jun; Day, W Antony et al. (2011) Alpha-COPI coatomer protein is required for rough endoplasmic reticulum whorl formation in mosquito midgut epithelial cells. PLoS One 6:e18150
Rascon Jr, Alberto A; Gearin, Johnathon; Isoe, Jun et al. (2011) In vitro activation and enzyme kinetic analysis of recombinant midgut serine proteases from the Dengue vector mosquito Aedes aegypti. BMC Biochem 12:43
Brackney, Doug E; Isoe, Jun; W C 4th, Black et al. (2010) Expression profiling and comparative analyses of seven midgut serine proteases from the yellow fever mosquito, Aedes aegypti. J Insect Physiol 56:736-44
Kelleher, Erin S; Pennington, James E (2009) Protease gene duplication and proteolytic activity in Drosophila female reproductive tracts. Mol Biol Evol 26:2125-34
Isoe, Jun; Rascon Jr, Alberto A; Kunz, Susan et al. (2009) Molecular genetic analysis of midgut serine proteases in Aedes aegypti mosquitoes. Insect Biochem Mol Biol 39:903-12
Isoe, Jun; Zamora, Jorge; Miesfeld, Roger L (2009) Molecular analysis of the Aedes aegypti carboxypeptidase gene family. Insect Biochem Mol Biol 39:68-73

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