Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032121-05
Application #
2067020
Study Section
Virology Study Section (VR)
Project Start
1992-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Cincinnati
Department
Genetics
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Divanovic, Senad; Sawtell, Nancy M; Trompette, Aurelien et al. (2012) Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection. J Infect Dis 205:152-61
Thompson, Richard L; Sawtell, Nancy M (2011) The herpes simplex virus type 1 latency associated transcript locus is required for the maintenance of reactivation competent latent infections. J Neurovirol 17:552-8
Sawtell, Nancy M; Triezenberg, Steven J; Thompson, Richard L (2011) VP16 serine 375 is a critical determinant of herpes simplex virus exit from latency in vivo. J Neurovirol 17:546-51
Thompson, Richard L; Sawtell, Nancy M (2010) Therapeutic implications of new insights into the critical role of VP16 in initiating the earliest stages of HSV reactivation from latency. Future Med Chem 2:1099-105
Thompson, Richard L; Preston, Chris M; Sawtell, Nancy M (2009) De novo synthesis of VP16 coordinates the exit from HSV latency in vivo. PLoS Pathog 5:e1000352
Holman, Holly A; MacLean, Alasdair R (2008) Neurovirulent factor ICP34.5 uniquely expressed in the herpes simplex virus type 1 Delta gamma 1 34.5 mutant 1716. J Neurovirol 14:28-40
Sawtell, N M; Thompson, R L; Haas, R L (2006) Herpes simplex virus DNA synthesis is not a decisive regulatory event in the initiation of lytic viral protein expression in neurons in vivo during primary infection or reactivation from latency. J Virol 80:38-50
Thompson, R L; Sawtell, N M (2006) Evidence that the herpes simplex virus type 1 ICP0 protein does not initiate reactivation from latency in vivo. J Virol 80:10919-30
Thompson, R L; Shieh, May T; Sawtell, N M (2003) Analysis of herpes simplex virus ICP0 promoter function in sensory neurons during acute infection, establishment of latency, and reactivation in vivo. J Virol 77:12319-30
Sawtell, N M (2003) Quantitative analysis of herpes simplex virus reactivation in vivo demonstrates that reactivation in the nervous system is not inhibited at early times postinoculation. J Virol 77:4127-38

Showing the most recent 10 out of 14 publications