Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI032983-01A2S2
Application #
2067941
Study Section
Virology Study Section (VR)
Project Start
1994-05-01
Project End
1997-04-30
Budget Start
1994-05-01
Budget End
1995-04-30
Support Year
1
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Westcott, Marlena M; Liu, Jingfang; Rajani, Karishma et al. (2015) Interferon Beta and Interferon Alpha 2a Differentially Protect Head and Neck Cancer Cells from Vesicular Stomatitis Virus-Induced Oncolysis. J Virol 89:7944-54
Yu, Nanmeng; Puckett, Shelby; Antinozzi, Peter A et al. (2015) Changes in Susceptibility to Oncolytic Vesicular Stomatitis Virus during Progression of Prostate Cancer. J Virol 89:5250-63
Smedberg, Jason R; Westcott, Marlena M; Ahmed, Maryam et al. (2014) Signaling pathways in murine dendritic cells that regulate the response to vesicular stomatitis virus vectors that express flagellin. J Virol 88:777-85
Blackham, Aaron U; Northrup, Scott A; Willingham, Mark et al. (2014) Molecular determinants of susceptibility to oncolytic vesicular stomatitis virus in pancreatic adenocarcinoma. J Surg Res 187:412-26
Blackham, Aaron U; Northrup, Scott A; Willingham, Mark et al. (2013) Variation in susceptibility of human malignant melanomas to oncolytic vesicular stomatitis virus. Surgery 153:333-43
Westcott, Marlena M; Ahmed, Maryam; Smedberg, Jason R et al. (2013) Preservation of dendritic cell function during vesicular stomatitis virus infection reflects both intrinsic and acquired mechanisms of resistance to suppression of host gene expression by viral M protein. J Virol 87:11730-40
Stewart 4th, J H; Ahmed, M; Northrup, S A et al. (2011) Vesicular stomatitis virus as a treatment for colorectal cancer. Cancer Gene Ther 18:837-49
Gerlier, Denis; Lyles, Douglas S (2011) Interplay between innate immunity and negative-strand RNA viruses: towards a rational model. Microbiol Mol Biol Rev 75:468-90, second page of table of
Cary, Zachary D; Willingham, Mark C; Lyles, Douglas S (2011) Oncolytic vesicular stomatitis virus induces apoptosis in U87 glioblastoma cells by a type II death receptor mechanism and induces cell death and tumor clearance in vivo. J Virol 85:5708-17
Ahmed, M; Puckett, S; Lyles, D S (2010) Susceptibility of breast cancer cells to an oncolytic matrix (M) protein mutant of vesicular stomatitis virus. Cancer Gene Ther 17:883-92

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