Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033049-11
Application #
6763095
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Duncan, Rory A
Project Start
1992-12-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
11
Fiscal Year
2004
Total Cost
$296,000
Indirect Cost
Name
University of Texas Austin
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
170230239
City
Austin
State
TX
Country
United States
Zip Code
78712
Guo, Pengfei; Szaniszlo, Paul J (2011) RNA interference of WdFKS1 mRNA expression causes slowed growth, incomplete septation and loss of cell wall integrity in yeast cells of the polymorphic, pathogenic fungus Wangiella (Exophiala) dermatitidis. Med Mycol 49:806-18
Wang, Qin; Szaniszlo, Paul J (2009) Roles of the pH signaling transcription factor PacC in Wangiella (Exophiala) dermatitidis. Fungal Genet Biol 46:657-66
Abramczyk, Dariusz; Park, Changwon; Szaniszlo, Paul J (2009) Cytolocalization of the class V chitin synthase in the yeast, hyphal and sclerotic morphotypes of Wangiella (Exophiala) dermatitidis. Fungal Genet Biol 46:28-41
Abramczyk, Dariusz; Szaniszlo, Paul J (2009) Immunoaffinity purification of the class V chitin synthase of Wangiella (Exophiala) dermatitidis. Prep Biochem Biotechnol 39:277-88
Wheeler, Michael H; Abramczyk, Dariusz; Puckhaber, Lorraine S et al. (2008) New biosynthetic step in the melanin pathway of Wangiella (Exophiala) dermatitidis: evidence for 2-acetyl-1,3,6,8-Tetrahydroxynaphthalene as a novel precursor. Eukaryot Cell 7:1699-711
Liu, Hongbo; Abramczyk, Dariusz; Cooper Jr, Chester R et al. (2008) Molecular cloning and characterization of WdTUP1, a gene that encodes a potential transcriptional repressor important for yeast-hyphal transitions in Wangiella (Exophiala) dermatitidis. Fungal Genet Biol 45:646-56
Liu, Hongbo; Szaniszlo, Paul J (2007) Transcription and expression analyses of WdCHS5, which encodes a class V chitin synthase with a myosin motor-like domain in Wangiella (Exophiala) dermatitidis. FEMS Microbiol Lett 276:99-105
Wang, Qin; Szaniszlo, Paul J (2007) WdStuAp, an APSES transcription factor, is a regulator of yeast-hyphal transitions in Wangiella (Exophiala) dermatitidis. Eukaryot Cell 6:1595-605
Zheng, Li; Mendoza, Leonel; Wang, Zheng et al. (2006) WdChs1p, a class II chitin synthase, is more responsible than WdChs2p (Class I) for normal yeast reproductive growth in the polymorphic, pathogenic fungus Wangiella (Exophiala) dermatitidis. Arch Microbiol 185:316-29
Paolo Jr, William F; Dadachova, Ekaterina; Mandal, Piyali et al. (2006) Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature. BMC Microbiol 6:55

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