Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034503-10
Application #
6686342
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Rubin, Fran A
Project Start
1994-12-01
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
10
Fiscal Year
2004
Total Cost
$185,625
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Wang, Beinan; Li, Shaoying; Dedhar, Shoukat et al. (2007) Paxillin phosphorylation: bifurcation point downstream of integrin-linked kinase (ILK) in streptococcal invasion. Cell Microbiol 9:1519-28
Wang, Beinan; Yurecko, Ryan S; Dedhar, Shoukat et al. (2006) Integrin-linked kinase is an essential link between integrins and uptake of bacterial pathogens by epithelial cells. Cell Microbiol 8:257-66
Wang, Beinan; Li, Shaoying; Southern, Peter J et al. (2006) Streptococcal modulation of cellular invasion via TGF-beta1 signaling. Proc Natl Acad Sci U S A 103:2380-5
Rezcallah, Myrna S; Hodges, Kimberly; Gill, Darcy B et al. (2005) Engagement of CD46 and alpha5beta1 integrin by group A streptococci is required for efficient invasion of epithelial cells. Cell Microbiol 7:645-53
Zimmerlein, Bjorn; Park, Hae-Sun; Li, Shaoying et al. (2005) The M protein is dispensable for maturation of streptococcal cysteine protease SpeB. Infect Immun 73:859-64
Purushothaman, Sai Sudha; Park, Hae-Sun; Cleary, P Patrick (2004) Promotion of fibronectin independent invasion by C5a peptidase into epithelial cells in group A Streptococcus. Indian J Med Res 119 Suppl:44-7
Park, Hae-Sun; Costalonga, Massimo; Reinhardt, R Lee et al. (2004) Primary induction of CD4 T cell responses in nasal associated lymphoid tissue during group A streptococcal infection. Eur J Immunol 34:2843-53
Purushothaman, Sai Sudha; Wang, Beinan; Cleary, P Patrick (2003) M1 protein triggers a phosphoinositide cascade for group A Streptococcus invasion of epithelial cells. Infect Immun 71:5823-30
Park, Hae-Sun; Francis, Kevin P; Yu, Jun et al. (2003) Membranous cells in nasal-associated lymphoid tissue: a portal of entry for the respiratory mucosal pathogen group A streptococcus. J Immunol 171:2532-7
Cue, D; Lam, H; Cleary, P P (2001) Genetic dissection of the Streptococcus pyogenes M1 protein: regions involved in fibronectin binding and intracellular invasion. Microb Pathog 31:231-42

Showing the most recent 10 out of 18 publications