Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI034867-05S1
Application #
2710490
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1994-01-01
Project End
2002-12-31
Budget Start
1998-01-01
Budget End
1998-12-31
Support Year
5
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Yale University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Mittra, Bidyottam; Cortez, Mauro; Haydock, Andrew et al. (2013) Iron uptake controls the generation of Leishmania infective forms through regulation of ROS levels. J Exp Med 210:401-16
Mittra, Bidyottam; Andrews, Norma W (2013) IRONy OF FATE: role of iron-mediated ROS in Leishmania differentiation. Trends Parasitol 29:489-96
Fernandes, Maria CecĂ­lia; Andrade, Leonardo Rodrigues de; Andrews, Norma Windsor et al. (2011) Trypanosoma cruzi trypomastigotes induce cytoskeleton modifications during HeLa cell invasion. Mem Inst Oswaldo Cruz 106:1014-6
Albertti, L A G; Macedo, A M; Chiari, E et al. (2010) Role of host lysosomal associated membrane protein (LAMP) in Trypanosoma cruzi invasion and intracellular development. Microbes Infect 12:784-9
da Silva, Claudio V; Kawashita, Silvia Y; Probst, Christian M et al. (2009) Characterization of a 21kDa protein from Trypanosoma cruzi associated with mammalian cell invasion. Microbes Infect 11:563-70
Chakrabarti, Sabyasachi; Andrade, Luciana O; Andrews, Norma W (2005) Trypanosoma cruzi invades synaptotagmin VII-deficient cells by a PI-3 kinase independent pathway. Mol Biochem Parasitol 141:125-8
Roy, Deepannita; Liston, David R; Idone, Vincent J et al. (2004) A process for controlling intracellular bacterial infections induced by membrane injury. Science 304:1515-8
Andrade, Luciana O; Andrews, Norma W (2004) Lysosomal fusion is essential for the retention of Trypanosoma cruzi inside host cells. J Exp Med 200:1135-43
Jaiswal, Jyoti K; Chakrabarti, Sabyasachi; Andrews, Norma W et al. (2004) Synaptotagmin VII restricts fusion pore expansion during lysosomal exocytosis. PLoS Biol 2:E233
Huynh, Chau; Andrews, Norma W (2003) Leishmania amazonensis Rab7 promotes toxicity of the amino acid ester Leu-OMe in amastigote megasomes. Mol Biochem Parasitol 132:101-4

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