Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI034893-05
Application #
2633536
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1994-01-01
Project End
1998-12-31
Budget Start
1997-09-01
Budget End
1997-12-31
Support Year
5
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Harvard University
Department
Pathology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Artavanis-Tsakonas, Katerina; Kasperkovitz, Pia V; Papa, Eliseo et al. (2011) The tetraspanin CD82 is specifically recruited to fungal and bacterial phagosomes prior to acidification. Infect Immun 79:1098-106
Vyas, Jatin M; Van der Veen, Annemarthe G; Ploegh, Hidde L (2008) The known unknowns of antigen processing and presentation. Nat Rev Immunol 8:607-18
Park, Boyoun; Brinkmann, Melanie M; Spooner, Eric et al. (2008) Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nat Immunol 9:1407-14
Vyas, Jatin M; Kim, You-Me; Artavanis-Tsakonas, Katerina et al. (2007) Tubulation of class II MHC compartments is microtubule dependent and involves multiple endolysosomal membrane proteins in primary dendritic cells. J Immunol 178:7199-210
Artavanis-Tsakonas, Katerina; Love, J Christopher; Ploegh, Hidde L et al. (2006) Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification. Proc Natl Acad Sci U S A 103:15945-50
Misaghi, Shahram; Balsara, Zarine R; Catic, Andre et al. (2006) Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection. Mol Microbiol 61:142-50
Gil-Torregrosa, Beatriz C; Lennon-Dumenil, Ana Maria; Kessler, Benedikt et al. (2004) Control of cross-presentation during dendritic cell maturation. Eur J Immunol 34:398-407
Lennon-Dumenil, Ana-Maria; Bakker, Arnold H; Maehr, Rene et al. (2002) Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation. J Exp Med 196:529-40
Fiebiger, Edda; Maehr, Rene; Villadangos, Jose et al. (2002) Invariant chain controls the activity of extracellular cathepsin L. J Exp Med 196:1263-9
Driessen, C; Lennon-Dumenil, A M; Ploegh, H L (2001) Individual cathepsins degrade immune complexes internalized by antigen-presenting cells via Fcgamma receptors. Eur J Immunol 31:1592-601

Showing the most recent 10 out of 26 publications