Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI035257-04
Application #
2070802
Study Section
Special Emphasis Panel (SRC (36))
Project Start
1993-09-30
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Public Health Research Institute
Department
Type
DUNS #
City
Newark
State
NY
Country
United States
Zip Code
Han, Xiulin; Dorsey-Oresto, Angella; Malik, Muhammad et al. (2010) Escherichia coli genes that reduce the lethal effects of stress. BMC Microbiol 10:35
Malik, Muhammad; Capecci, Joseph; Drlica, Karl (2009) Lon protease is essential for paradoxical survival of Escherichia coli exposed to high concentrations of quinolone. Antimicrob Agents Chemother 53:3103-5
Drlica, Karl; Hiasa, Hiroshi; Kerns, Robert et al. (2009) Quinolones: action and resistance updated. Curr Top Med Chem 9:981-98
Hussain, Syed; Malik, Muhammad; Shi, Lanbo et al. (2009) In vitro model of mycobacterial growth arrest using nitric oxide with limited air. Antimicrob Agents Chemother 53:157-61
Usongo, Valentine; Nolent, Flora; Sanscartier, Patrick et al. (2008) Depletion of RNase HI activity in Escherichia coli lacking DNA topoisomerase I leads to defects in DNA supercoiling and segregation. Mol Microbiol 69:968-81
Zhao, Xilin; Drlica, Karl (2008) A unified anti-mutant dosing strategy. J Antimicrob Chemother 62:434-6
Drlica, Karl; Zhao, Xilin; Kreiswirth, Barry (2008) Minimising moxifloxacin resistance with tuberculosis. Lancet Infect Dis 8:273-5
Drlica, Karl; Malik, Muhammad; Kerns, Robert J et al. (2008) Quinolone-mediated bacterial death. Antimicrob Agents Chemother 52:385-92
Baaklini, Imad; Usongo, Valentine; Nolent, Flora et al. (2008) Hypernegative supercoiling inhibits growth by causing RNA degradation. J Bacteriol 190:7346-56
German, Nadezhda; Malik, Muhammad; Rosen, Jonathan D et al. (2008) Use of gyrase resistance mutants to guide selection of 8-methoxy-quinazoline-2,4-diones. Antimicrob Agents Chemother 52:3915-21

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