Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI035950-03
Application #
2071944
Study Section
Special Emphasis Panel (SRC (83))
Project Start
1994-05-01
Project End
1996-07-31
Budget Start
1996-02-01
Budget End
1996-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Physiology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Davis, Michael J; Gregorka, Brian; Gestwicki, Jason E et al. (2012) Inducible renitence limits Listeria monocytogenes escape from vacuoles in macrophages. J Immunol 189:4488-95
Radtke, Andrea L; Anderson, Kelsi L; Davis, Michael J et al. (2011) Listeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome. Proc Natl Acad Sci U S A 108:1633-8
Davis, Michael J; Swanson, Joel A (2010) Technical advance: Caspase-1 activation and IL-1? release correlate with the degree of lysosome damage, as illustrated by a novel imaging method to quantify phagolysosome damage. J Leukoc Biol 88:813-22
Ballinger, Megan N; Welliver, Timothy; Straight, Samuel et al. (2010) Transient increase in cyclic AMP localized to macrophage phagosomes. PLoS One 5:e13962
Zhang, Youxin; Hoppe, Adam D; Swanson, Joel A (2010) Coordination of Fc receptor signaling regulates cellular commitment to phagocytosis. Proc Natl Acad Sci U S A 107:19332-7
Beemiller, Peter; Zhang, Youxin; Mohan, Suresh et al. (2010) A Cdc42 activation cycle coordinated by PI 3-kinase during Fc receptor-mediated phagocytosis. Mol Biol Cell 21:470-80
Yoshida, Sei; Hoppe, Adam D; Araki, Nobukazu et al. (2009) Sequential signaling in plasma-membrane domains during macropinosome formation in macrophages. J Cell Sci 122:3250-61
Heinsbroek, Sigrid E M; Kamen, Lynn A; Taylor, Philip R et al. (2009) Actin and phosphoinositide recruitment to fully formed Candida albicans phagosomes in mouse macrophages. J Innate Immun 1:244-53
Hoppe, Adam D; Seveau, Stephanie; Swanson, Joel A (2009) Live cell fluorescence microscopy to study microbial pathogenesis. Cell Microbiol 11:540-50
Swanson, Joel A (2008) Shaping cups into phagosomes and macropinosomes. Nat Rev Mol Cell Biol 9:639-49

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