Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI036199-03
Application #
2072334
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1994-08-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Sokolskaja, Elena; Olivari, Silvia; Zufferey, Madeleine et al. (2010) Cyclosporine blocks incorporation of HIV-1 envelope glycoprotein into virions. J Virol 84:4851-5
Mangeat, Bastien; Gers-Huber, Gustavo; Lehmann, Martin et al. (2009) HIV-1 Vpu neutralizes the antiviral factor Tetherin/BST-2 by binding it and directing its beta-TrCP2-dependent degradation. PLoS Pathog 5:e1000574
Sebastian, Sarah; Grutter, Christian; Strambio de Castillia, Caterina et al. (2009) An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding. J Virol 83:3365-73
Strebel, Klaus; Luban, Jeremy; Jeang, Kuan-Teh (2009) Human cellular restriction factors that target HIV-1 replication. BMC Med 7:48
Neagu, Martha R; Ziegler, Patrick; Pertel, Thomas et al. (2009) Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J Clin Invest 119:3035-47
Kaul, Artur; Stauffer, Sarah; Berger, Carola et al. (2009) Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics. PLoS Pathog 5:e1000546
Santoni de Sio, Francesca Romana; Gritti, Angela; Cascio, Paolo et al. (2008) Lentiviral vector gene transfer is limited by the proteasome at postentry steps in various types of stem cells. Stem Cells 26:2142-52
Goujon, Caroline; Arfi, Vanessa; Pertel, Thomas et al. (2008) Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells. J Virol 82:12335-45
Luban, Jeremy (2007) Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection. J Virol 81:1054-61
Berthoux, Lionel; Sebastian, Sarah; Muesing, Mark A et al. (2007) The role of lysine 186 in HIV-1 integrase multimerization. Virology 364:227-36

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