Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI036680-01A3
Application #
2073113
Study Section
AIDS and Related Research Study Section 5 (ARRE)
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
McNair, Nina N; Mead, Jan R (2013) CD4? effector and memory cell populations protect against Cryptosporidium parvum infection. Microbes Infect 15:599-606
Bedi, B; Mead, J R (2012) Cryptosporidium parvum antigens induce mouse and human dendritic cells to generate Th1-enhancing cytokines. Parasite Immunol 34:473-85
Benitez, Alvaro; Priest, Jeffrey W; Ehigiator, Humphrey N et al. (2011) Evaluation of DNA encoding acidic ribosomal protein P2 of Cryptosporidium parvum as a potential vaccine candidate for cryptosporidiosis. Vaccine 29:9239-45
Mead, Jan R (2010) Challenges and prospects for a Cryptosporidium vaccine. Future Microbiol 5:335-7
Benitez, Alvaro J; McNair, Nina; Mead, Jan R (2009) Oral immunization with attenuated Salmonella enterica serovar Typhimurium encoding Cryptosporidium parvum Cp23 and Cp40 antigens induces a specific immune response in mice. Clin Vaccine Immunol 16:1272-8
Ehigiator, Humphrey N; Romagnoli, Pablo; Priest, Jeffrey W et al. (2007) Induction of murine immune responses by DNA encoding a 23-kDa antigen of Cryptosporidium parvum. Parasitol Res 101:943-50
Ehigiator, Humphrey N; McNair, Nina; Mead, Jan R (2007) Cryptosporidium parvum: the contribution of Th1-inducing pathways to the resolution of infection in mice. Exp Parasitol 115:107-13
Ehigiator, H N; Romagnoli, P; Borgelt, K et al. (2005) Mucosal cytokine and antigen-specific responses to Cryptosporidium parvum in IL-12p40 KO mice. Parasite Immunol 27:17-28
Smith, L M; Bonafonte, M T; Mead, J R (2000) Cytokine expression and specific lymphocyte proliferation in two strains of Cryptosporidium parvum-infected gamma-interferon knockout mice. J Parasitol 86:300-7
Bonafonte, M T; Smith, L M; Mead, J R (2000) A 23-kDa recombinant antigen of Cryptosporidium parvum induces a cellular immune response on in vitro stimulated spleen and mesenteric lymph node cells from infected mice. Exp Parasitol 96:32-41

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