Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037141-02
Application #
2073772
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1995-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Wang, Su He; Fan, Yongyi; Makidon, Paul E et al. (2012) Induction of immune tolerance in mice with a novel mucosal nanoemulsion adjuvant and self-antigen. Nanomedicine (Lond) 7:867-76
Wang, Su He; Chen, Gwo-Hsiao; Fan, Yongyi et al. (2009) Tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis by the expansion of CD4+CD25+ regulatory T cells. Endocrinology 150:2000-7
Wang, Su He; Shi, Xiangyang; Chen, Xisui et al. (2009) Therapeutic efficacy of 2-methoxyestradiol microcrystals encapsulated within polyelectrolyte multilayers. Macromol Biosci 9:429-36
Wang, Su He; Van Antwerp, Mary; Kuick, Rork et al. (2007) Microarray analysis of cytokine activation of apoptosis pathways in the thyroid. Endocrinology 148:4844-52
Wang, Su He; Arscott, Patricia; Wu, Peiqing et al. (2006) No apparent damage in the thyroid of transgenic mice expressing antiapoptotic FLIP. Thyroid 16:1-8
Wang, Su He; Cao, Zhengyi; Wolf, Julie M et al. (2005) Death ligand tumor necrosis factor-related apoptosis-inducing ligand inhibits experimental autoimmune thyroiditis. Endocrinology 146:4721-6
Wang, Su He; Bretz, James D; Phelps, Ellen et al. (2002) A unique combination of inflammatory cytokines enhances apoptosis of thyroid follicular cells and transforms nondestructive to destructive thyroiditis in experimental autoimmune thyroiditis. J Immunol 168:2470-4
Bretz, J D; Baker Jr, J R (2001) Apoptosis and autoimmune thyroid disease: following a TRAIL to thyroid destruction? Clin Endocrinol (Oxf) 55:1-11
Wang, S H; Phelps, E; Utsugi, S et al. (2001) Susceptibility of thyroid cancer cells to 7-hydroxystaurosporine-induced apoptosis correlates with Bcl-2 protein level. Thyroid 11:725-31
Phelps, E; Wu, P; Bretz, J et al. (2000) Thyroid cell apoptosis. A new understanding of thyroid autoimmunity. Endocrinol Metab Clin North Am 29:375-88, viii

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