Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037606-02
Application #
2074427
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1995-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Martinez de la Peña, Claudia F; De Masi, Leon; Nisa, Shahista et al. (2016) BfpI, BfpJ, and BfpK Minor Pilins Are Important for the Function and Biogenesis of Bundle-Forming Pili Expressed by Enteropathogenic Escherichia coli. J Bacteriol 198:846-56
Lieberman, Joshua A; Petro, Courtney D; Thomas, Stefani et al. (2015) Type IV pilus secretins have extracellular C termini. MBio 6:
Yamagata, Atsushi; Milgotina, Ekaterina; Scanlon, Karen et al. (2012) Structure of an essential type IV pilus biogenesis protein provides insights into pilus and type II secretion systems. J Mol Biol 419:110-24
Aroeti, Benjamin; Friedman, Gil; Zlotkin-Rivkin, Efrat et al. (2012) Retraction of enteropathogenic E. coli type IV pili promotes efficient host cell colonization, effector translocation and tight junction disruption. Gut Microbes 3:267-71
De Masi, Leon; Szmacinski, Henryk; Schreiber, Wiebke et al. (2012) BfpL is essential for type IV bundle-forming pilus biogenesis and interacts with the periplasmic face of BfpC. Microbiology 158:2515-26
Lieberman, Joshua A; Frost, Nicholas A; Hoppert, Michael et al. (2012) Outer membrane targeting, ultrastructure, and single molecule localization of the enteropathogenic Escherichia coli type IV pilus secretin BfpB. J Bacteriol 194:1646-58
Zahavi, Eitan E; Lieberman, Joshua A; Donnenberg, Michael S et al. (2011) Bundle-forming pilus retraction enhances enteropathogenic Escherichia coli infectivity. Mol Biol Cell 22:2436-47
Milgotina, Ekaterina I; Lieberman, Joshua A; Donnenberg, Michael S (2011) The inner membrane subassembly of the enteropathogenic Escherichia coli bundle-forming pilus machine. Mol Microbiol 81:1125-7
Humphries, Romney M; Griener, Thomas P; Vogt, Stefanie L et al. (2010) N-acetyllactosamine-induced retraction of bundle-forming pili regulates virulence-associated gene expression in enteropathogenic Escherichia coli. Mol Microbiol 76:1111-26
Vogt, Stefanie L; Nevesinjac, Anna Z; Humphries, Romney M et al. (2010) The Cpx envelope stress response both facilitates and inhibits elaboration of the enteropathogenic Escherichia coli bundle-forming pilus. Mol Microbiol 76:1095-110

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