Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI037750-01A2
Application #
2004255
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1996-09-01
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Veterinary Sciences
Type
Other Domestic Higher Education
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Hayakawa, Yoku; Jin, Guangchun; Wang, Hongshan et al. (2015) CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. Gut 64:544-53
Lertpiriyapong, Kvin; Whary, Mark T; Muthupalani, Sureshkumar et al. (2014) Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis. Gut 63:54-63
Whary, Mark T; Muthupalani, Sureshkumar; Ge, Zhongming et al. (2014) Helminth co-infection in Helicobacter pylori infected INS-GAS mice attenuates gastric premalignant lesions of epithelial dysplasia and glandular atrophy and preserves colonization resistance of the stomach to lower bowel microbiota. Microbes Infect 16:345-55
Weis, Victoria G; Sousa, Josane F; LaFleur, Bonnie J et al. (2013) Heterogeneity in mouse spasmolytic polypeptide-expressing metaplasia lineages identifies markers of metaplastic progression. Gut 62:1270-9
Ek, Courtney; Whary, Mark T; Ihrig, Melanie et al. (2012) Serologic evidence that ascaris and toxoplasma infections impact inflammatory responses to Helicobacter pylori in Colombians. Helicobacter 17:107-15
Ohtani, Masahiro; Ge, Zhongming; Garcia, Alexis et al. (2011) 17 ýý-estradiol suppresses Helicobacter pylori-induced gastric pathology in male hypergastrinemic INS-GAS mice. Carcinogenesis 32:1244-50
Lofgren, Jennifer L; Whary, Mark T; Ge, Zhongming et al. (2011) Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology 140:210-20
Sheh, Alexander; Ge, Zhongming; Parry, Nicola M A et al. (2011) 17?-estradiol and tamoxifen prevent gastric cancer by modulating leukocyte recruitment and oncogenic pathways in Helicobacter pylori-infected INS-GAS male mice. Cancer Prev Res (Phila) 4:1426-35
Seo, Ji Hye; Fox, James G; Peek Jr, Richard M et al. (2011) N-methyl D-aspartate channels link ammonia and epithelial cell death mechanisms in Helicobacter pylori Infection. Gastroenterology 141:2064-75
Patterson, Mary M; Rogers, Arlin B; Fox, James G (2010) Experimental Helicobacter marmotae infection in A/J mice causes enterohepatic disease. J Med Microbiol 59:1235-41

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