Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI038474-02
Application #
2075525
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1994-12-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pathology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Fiege, Jessica K; Beura, Lalit K; Burbach, Brandon J et al. (2016) Adhesion- and Degranulation-Promoting Adapter Protein Promotes CD8 T Cell Differentiation and Resident Memory Formation and Function during an Acute Infection. J Immunol 197:2079-89
Fiege, Jessica K; Burbach, Brandon J; Shimizu, Yoji (2015) Negative Regulation of Memory Phenotype CD8 T Cell Conversion by Adhesion and Degranulation-Promoting Adapter Protein. J Immunol 195:3119-28
Mitchell, Jason S; Burbach, Brandon J; Srivastava, Rupa et al. (2013) Multistage T cell-dendritic cell interactions control optimal CD4 T cell activation through the ADAP-SKAP55-signaling module. J Immunol 191:2372-83
Zumwalde, Nicholas A; Domae, Eisuke; Mescher, Matthew F et al. (2013) ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation. J Immunol 191:3681-93
Srivastava, Rupa; Burbach, Brandon J; Mitchell, Jason S et al. (2012) ADAP regulates cell cycle progression of T cells via control of cyclin E and Cdk2 expression through two distinct CARMA1-dependent signaling pathways. Mol Cell Biol 32:1908-17
Burbach, Brandon J; Srivastava, Rupa; Ingram, Melissa A et al. (2011) The pleckstrin homology domain in the SKAP55 adapter protein defines the ability of the adapter protein ADAP to regulate integrin function and NF-kappaB activation. J Immunol 186:6227-37
Bunnell, Tina M; Burbach, Brandon J; Shimizu, Yoji et al. (2011) ?-Actin specifically controls cell growth, migration, and the G-actin pool. Mol Biol Cell 22:4047-58
Srivastava, Rupa; Burbach, Brandon J; Shimizu, Yoji (2010) NF-kappaB activation in T cells requires discrete control of IkappaB kinase alpha/beta (IKKalpha/beta) phosphorylation and IKKgamma ubiquitination by the ADAP adapter protein. J Biol Chem 285:11100-5
Denucci, Christopher C; Mitchell, Jason S; Shimizu, Yoji (2009) Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there. Crit Rev Immunol 29:87-109
Burbach, Brandon J; Srivastava, Rupa; Medeiros, Ricardo B et al. (2008) Distinct regulation of integrin-dependent T cell conjugate formation and NF-kappa B activation by the adapter protein ADAP. J Immunol 181:4840-51

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