Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI038996-07S1
Application #
6709162
Study Section
Allergy and Immunology Study Section (ALY)
Program Officer
Gondre-Lewis, Timothy A
Project Start
1996-02-01
Project End
2007-02-28
Budget Start
2003-03-01
Budget End
2004-02-29
Support Year
7
Fiscal Year
2003
Total Cost
$87,502
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Pathology
Type
Schools of Medicine
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
Clement, Cristina C; Wang, Wei; Dzieciatkowska, Monika et al. (2018) Quantitative Profiling of the Lymph Node Clearance Capacity. Sci Rep 8:11253
Zimmermann, Kerstin; Eells, Rebecca; Heinrich, Frank et al. (2017) The cytosolic domain of T-cell receptor ? associates with membranes in a dynamic equilibrium and deeply penetrates the bilayer. J Biol Chem 292:17746-17759
Song, InYoung; Gil, Anna; Mishra, Rabinarayan et al. (2017) Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope. Nat Struct Mol Biol 24:395-406
Stamogiannos, Athanasios; Maben, Zachary; Papakyriakou, Athanasios et al. (2017) Critical Role of Interdomain Interactions in the Conformational Change and Catalytic Mechanism of Endoplasmic Reticulum Aminopeptidase 1. Biochemistry 56:1546-1558
Hellman, Lance M; Yin, Liusong; Wang, Yuan et al. (2016) Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes. J Immunol Methods 432:95-101
Clement, Cristina C; Moncrieffe, Halima; Lele, Aditi et al. (2016) Autoimmune response to transthyretin in juvenile idiopathic arthritis. JCI Insight 1:
Stern, Lawrence J; Santambrogio, Laura (2016) The melting pot of the MHC II peptidome. Curr Opin Immunol 40:70-7
Clement, Cristina C; Becerra, Aniuska; Yin, Liusong et al. (2016) The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity. J Biol Chem 291:5576-95
Yin, Liusong; Maben, Zachary J; Becerra, Aniuska et al. (2015) Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions. J Immunol 195:706-16
Stadinski, Brian D; Trenh, Peter; Duke, Brian et al. (2014) Effect of CDR3 sequences and distal V gene residues in regulating TCR-MHC contacts and ligand specificity. J Immunol 192:6071-82

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