Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI039654-01
Application #
2076695
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1996-06-01
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Kovacikova, Gabriela; Lin, Wei; Taylor, Ronald K et al. (2017) The Fatty Acid Regulator FadR Influences the Expression of the Virulence Cascade in the El Tor Biotype of Vibrio cholerae by Modulating the Levels of ToxT via Two Different Mechanisms. J Bacteriol 199:
Privett, Britney R; Pellegrini, Maria; Kovacikova, Gabriela et al. (2017) Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae. Biochemistry 56:3840-3849
Midgett, Charles R; Almagro-Moreno, Salvador; Pellegrini, Maria et al. (2017) Bile salts and alkaline pH reciprocally modulate the interaction between the periplasmic domains of Vibrio cholerae ToxR and ToxS. Mol Microbiol 105:258-272
Shi, Wei; Kovacikova, Gabriela; Lin, Wei et al. (2015) The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand. Nat Commun 6:6032
Almagro-Moreno, Salvador; Kim, Tae K; Skorupski, Karen et al. (2015) Proteolysis of virulence regulator ToxR is associated with entry of Vibrio cholerae into a dormant state. PLoS Genet 11:e1005145
Almagro-Moreno, Salvador; Pruss, Kali; Taylor, Ronald K (2015) Intestinal Colonization Dynamics of Vibrio cholerae. PLoS Pathog 11:e1004787
Almagro-Moreno, Salvador; Root, Michael Z; Taylor, Ronald K (2015) Role of ToxS in the proteolytic cascade of virulence regulator ToxR in Vibrio cholerae. Mol Microbiol 98:963-76
Almagro-Moreno, Salvador; Taylor, Ronald K (2013) Cholera: Environmental Reservoirs and Impact on Disease Transmission. Microbiol Spectr 1:
Cerda-Maira, Francisca A; Kovacikova, Gabriela; Jude, Brooke A et al. (2013) Characterization of BreR interaction with the bile response promoters breAB and breR in Vibrio cholerae. J Bacteriol 195:307-17
Taylor, Jennifer L; De Silva, Rukman S; Kovacikova, Gabriela et al. (2012) The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH. Mol Microbiol 83:457-70

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