Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI040101-01
Application #
2077030
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Lakritz, Jessica R; Thibault, Derek M; Robinson, Jake A et al. (2016) ?4-Integrin Antibody Treatment Blocks Monocyte/Macrophage Traffic to, Vascular Cell Adhesion Molecule-1 Expression in, and Pathology of the Dorsal Root Ganglia in an SIV Macaque Model of HIV-Peripheral Neuropathy. Am J Pathol 186:1754-1761
Lakritz, Jessica R; Robinson, Jake A; Polydefkis, Michael J et al. (2015) Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins. J Neuroinflammation 12:237
Nowlin, Brian T; Burdo, Tricia H; Midkiff, Cecily C et al. (2015) SIV encephalitis lesions are composed of CD163(+) macrophages present in the central nervous system during early SIV infection and SIV-positive macrophages recruited terminally with AIDS. Am J Pathol 185:1649-65
Lakritz, Jessica R; Bodair, Ayman; Shah, Neal et al. (2015) Monocyte Traffic, Dorsal Root Ganglion Histopathology, and Loss of Intraepidermal Nerve Fiber Density in SIV Peripheral Neuropathy. Am J Pathol 185:1912-23
Soulas, Caroline; Autissier, Patrick J; Burdo, Tricia H et al. (2015) Distinct phenotype, longitudinal changes of numbers and cell-associated virus in blood dendritic cells in SIV-infected CD8-lymphocyte depleted macaques. PLoS One 10:e0119764
Veesler, David; Khayat, Reza; Krishnamurthy, Srinath et al. (2014) Architecture of a dsDNA viral capsid in complex with its maturation protease. Structure 22:230-7
Veesler, David; Campbell, Melody G; Cheng, Anchi et al. (2013) Maximizing the potential of electron cryomicroscopy data collected using direct detectors. J Struct Biol 184:193-202
Ahsan, Muhammad H; Gill, Amy F; Alvarez, Xavier et al. (2013) Kinetics of liver macrophages (Kupffer cells) in SIV-infected macaques. Virology 446:77-85
Snijder, Joost; Rose, Rebecca J; Veesler, David et al. (2013) Studying 18 MDa virus assemblies with native mass spectrometry. Angew Chem Int Ed Engl 52:4020-3
Johnson, John E (2013) Confessions of an icosahedral virus crystallographer. Microscopy (Oxf) 62:69-79

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