Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI041599-02
Application #
2673050
Study Section
Experimental Virology Study Section (EVR)
Project Start
1997-07-01
Project End
2001-06-30
Budget Start
1998-03-01
Budget End
1998-06-30
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Brookhaven National Laboratory
Department
Type
DUNS #
027579460
City
Upton
State
NY
Country
United States
Zip Code
11973

  Publications

Mangel, Walter F; McGrath, William J; Xiong, Kan et al. (2016) Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA. Nat Commun 7:10202
Turkin, Alexander; Zhang, Lei; Marcozzi, Alessio et al. (2016) Speeding up biomolecular interactions by molecular sledding. Chem Sci 7:916-920
Geertsema, Hylkje J; Schulte, Aartje C; Spenkelink, Lisanne M et al. (2015) Single-molecule imaging at high fluorophore concentrations by local activation of dye. Biophys J 108:949-956
Pérez-Berná, Ana J; Mangel, Walter F; McGrath, William J et al. (2014) Processing of the l1 52/55k protein by the adenovirus protease: a new substrate and new insights into virion maturation. J Virol 88:1513-24
Mangel, Walter F; San Martín, Carmen (2014) Structure, function and dynamics in adenovirus maturation. Viruses 6:4536-70
Graziano, Vito; McGrath, William J; Suomalainen, Maarit et al. (2013) Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: I. binding to DNA AND to hexon of the precursor to protein VI, pVI, of human adenovirus. J Biol Chem 288:2059-67
McGrath, William J; Graziano, Vito; Zabrocka, Katarzyna et al. (2013) First generation inhibitors of the adenovirus proteinase. FEBS Lett 587:2332-9
Baniecki, Mary Lynn; McGrath, William J; Mangel, Walter F (2013) Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: III. atomic resolution structure of the nascent form of the adenovirus proteinase. J Biol Chem 288:2081-91
Graziano, Vito; Luo, Guobin; Blainey, Paul C et al. (2013) Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: II. adenovirus proteinase is activated in an unusual one-dimensional biochemical reaction. J Biol Chem 288:2068-80
Blainey, Paul C; Graziano, Vito; Pérez-Berná, Ana J et al. (2013) Regulation of a viral proteinase by a peptide and DNA in one-dimensional space: IV. viral proteinase slides along DNA to locate and process its substrates. J Biol Chem 288:2092-102

Showing the most recent 10 out of 27 publications