Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI041769-07
Application #
6764213
Study Section
Special Emphasis Panel (ZRG1-SSS-W (03))
Program Officer
Kehn, Patricia J
Project Start
1997-05-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
7
Fiscal Year
2004
Total Cost
$360,259
Indirect Cost
Name
Stanford University
Department
Surgery
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
Harris-Arnold, A; Arnold, C P; Schaffert, S et al. (2015) Epstein-Barr virus modulates host cell microRNA-194 to promote IL-10 production and B lymphoma cell survival. Am J Transplant 15:2814-24
Hatton, Olivia L; Harris-Arnold, Aleishia; Schaffert, Steven et al. (2014) The interplay between Epstein-Barr virus and B lymphocytes: implications for infection, immunity, and disease. Immunol Res 58:268-76
Hatton, O; Lambert, S L; Phillips, L K et al. (2013) Syk-induced phosphatidylinositol-3-kinase activation in Epstein-Barr virus posttransplant lymphoproliferative disorder. Am J Transplant 13:883-890
Furukawa, S; Wei, L; Krams, S M et al. (2013) PI3K? inhibition augments the efficacy of rapamycin in suppressing proliferation of Epstein-Barr virus (EBV)+ B cell lymphomas. Am J Transplant 13:2035-43
Wei, L; Wang, M; Qu, X et al. (2012) Differential expression of microRNAs during allograft rejection. Am J Transplant 12:1113-23
Hatton, Olivia; Martinez, Olivia M; Esquivel, Carlos O (2012) Emerging therapeutic strategies for Epstein-Barr virus+ post-transplant lymphoproliferative disorder. Pediatr Transplant 16:220-9
Hatton, Olivia; Lambert, Stacie L; Krams, Sheri M et al. (2012) Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas. PLoS One 7:e42610
Hatton, Olivia; Phillips, Lori K; Vaysberg, Maria et al. (2011) Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+ (EBV+) B cell lymphomas. J Biol Chem 286:37368-78
Harris, A; Krams, S M; Martinez, O M (2010) MicroRNAs as immune regulators: implications for transplantation. Am J Transplant 10:713-9
Vaysberg, M; Lambert, S L; Krams, S M et al. (2009) Activation of the JAK/STAT pathway in Epstein Barr virus+-associated posttransplant lymphoproliferative disease: role of interferon-gamma. Am J Transplant 9:2292-302

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