Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI046756-03
Application #
6511200
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Program Officer
Kehn, Patricia J
Project Start
2000-04-01
Project End
2005-03-31
Budget Start
2002-04-01
Budget End
2003-03-31
Support Year
3
Fiscal Year
2002
Total Cost
$338,823
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Daly, Kevin P; Stack, Maria; Eisenga, Michele F et al. (2017) Vascular endothelial growth factor A is associated with the subsequent development of moderate or severe cardiac allograft vasculopathy in pediatric heart transplant recipients. J Heart Lung Transplant 36:434-442
Wedel, Johannes; Nakayama, Hironao; Kochupurakkal, Nora M et al. (2017) The intragraft microenvironment as a central determinant of chronic rejection or local immunoregulation/tolerance. Curr Opin Organ Transplant 22:55-63
Boneschansker, Leo; Nakayama, Hironao; Eisenga, Michele et al. (2016) Netrin-1 Augments Chemokinesis in CD4+ T Cells In Vitro and Elicits a Proinflammatory Response In Vivo. J Immunol 197:1389-98
Bruneau, Sarah; Wedel, Johannes; Fakhouri, Fadi et al. (2016) Translational implications of endothelial cell dysfunction in association with chronic allograft rejection. Pediatr Nephrol 31:41-51
Wedel, Johannes; Bruneau, Sarah; Kochupurakkal, Nora et al. (2015) Chronic allograft rejection: a fresh look. Curr Opin Organ Transplant 20:13-20
Daly, Kevin P; Dearling, Jason L J; Seto, Tatsuichiro et al. (2015) Use of [18F]FDG Positron Emission Tomography to Monitor the Development of Cardiac Allograft Rejection. Transplantation 99:e132-9
Boneschansker, Leo; Yan, Jun; Wong, Elisabeth et al. (2014) Microfluidic platform for the quantitative analysis of leukocyte migration signatures. Nat Commun 5:4787
Daly, Kevin P; Seifert, Michael E; Chandraker, Anil et al. (2013) VEGF-C, VEGF-A and related angiogenesis factors as biomarkers of allograft vasculopathy in cardiac transplant recipients. J Heart Lung Transplant 32:120-8
Bruneau, Sarah; Nakayama, Hironao; Woda, Craig B et al. (2013) DEPTOR regulates vascular endothelial cell activation and proinflammatory and angiogenic responses. Blood 122:1833-42
Bruneau, Sarah; Woda, Craig Bryan; Daly, Kevin Patrick et al. (2012) Key Features of the Intragraft Microenvironment that Determine Long-Term Survival Following Transplantation. Front Immunol 3:54

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