Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI048082-02
Application #
6703675
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Program Officer
Rogers, Martin J
Project Start
2003-02-15
Project End
2008-01-31
Budget Start
2004-02-01
Budget End
2005-01-31
Support Year
2
Fiscal Year
2004
Total Cost
$363,375
Indirect Cost
Name
Boston University
Department
Biochemistry
Type
Schools of Dentistry
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Aqeel, Yousuf; Rodriguez, Raquel; Chatterjee, Aparajita et al. (2017) Killing of diverse eye pathogens (Acanthamoeba spp., Fusarium solani, and Chlamydia trachomatis) with alcohols. PLoS Negl Trop Dis 11:e0005382
Samuelson, John; Robbins, Phillips W (2015) Effects of N-glycan precursor length diversity on quality control of protein folding and on protein glycosylation. Semin Cell Dev Biol 41:121-8
Chatterjee, Aparajita; Bandini, Giulia; Motari, Edwin et al. (2015) Ethanol and isopropanol in concentrations present in hand sanitizers sharply reduce excystation of Giardia and Entamoeba and eliminate oral infectivity of Giardia cysts in gerbils. Antimicrob Agents Chemother 59:6749-54
Bushkin, G Guy; Motari, Edwin; Carpentieri, Andrea et al. (2013) Evidence for a structural role for acid-fast lipids in oocyst walls of Cryptosporidium, Toxoplasma, and Eimeria. MBio 4:e00387-13
Samuelson, John; Bushkin, G Guy; Chatterjee, Aparajita et al. (2013) Strategies to discover the structural components of cyst and oocyst walls. Eukaryot Cell 12:1578-87
Bushkin, G Guy; Motari, Edwin; Magnelli, Paula et al. (2012) ýý-1,3-glucan, which can be targeted by drugs, forms a trabecular scaffold in the oocyst walls of Toxoplasma and Eimeria. MBio 3:
Samuelson, John; Robbins, Phillips (2011) A simple fibril and lectin model for cyst walls of Entamoeba and perhaps Giardia. Trends Parasitol 27:17-22
Mitra, Sanghamitra; Cui, Jike; Robbins, Phillips W et al. (2010) A deeply divergent phosphoglucomutase (PGM) of Giardia lamblia has both PGM and phosphomannomutase activities. Glycobiology 20:1233-40
Chatterjee, Aparajita; Carpentieri, Andrea; Ratner, Daniel M et al. (2010) Giardia cyst wall protein 1 is a lectin that binds to curled fibrils of the GalNAc homopolymer. PLoS Pathog 6:e1001059
Bushkin, G Guy; Ratner, Daniel M; Cui, Jike et al. (2010) Suggestive evidence for Darwinian Selection against asparagine-linked glycans of Plasmodium falciparum and Toxoplasma gondii. Eukaryot Cell 9:228-41

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