Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI053439-02S1
Application #
6908822
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Esch, Thomas R
Project Start
2004-07-01
Project End
2006-12-31
Budget Start
2004-07-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$31,528
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Pathology
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Mohiuddin, Imran H; Pillai, Vinodh; Baughman, Ethan J et al. (2016) Induction of regulatory T-cells from memory T-cells is perturbed during acute exacerbation of multiple sclerosis. Clin Immunol 166-167:12-8
Sinha, Sushmita; Crawford, Michael P; Ortega, Sterling B et al. (2015) Multiparameter Flow Cytometric Assays to Quantify Effector and Regulatory T-Cell Function in Multiple Sclerosis. J Mult Scler (Foster City) 2:
Sinha, Sushmita; Boyden, Alexander W; Itani, Farah R et al. (2015) CD8(+) T-Cells as Immune Regulators of Multiple Sclerosis. Front Immunol 6:619
Cunnusamy, Khrishen; Baughman, Ethan J; Franco, Jorge et al. (2014) Disease exacerbation of multiple sclerosis is characterized by loss of terminally differentiated autoregulatory CD8+ T cells. Clin Immunol 152:115-26
Sinha, Sushmita; Itani, Farah R; Karandikar, Nitin J (2014) Immune regulation of multiple sclerosis by CD8+ T cells. Immunol Res 59:254-65
Ortega, Sterling B; Kashi, Venkatesh P; Tyler, Andrew F et al. (2013) The disease-ameliorating function of autoregulatory CD8 T cells is mediated by targeting of encephalitogenic CD4 T cells in experimental autoimmune encephalomyelitis. J Immunol 191:117-26
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Biegler, Brian W; Yan, Shirley X; Ortega, Sterling B et al. (2011) Clonal composition of neuroantigen-specific CD8+ and CD4+ T-cells in multiple sclerosis. J Neuroimmunol 234:131-40
Baughman, Ethan J; Mendoza, Jason P; Ortega, Sterling B et al. (2011) Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis. J Autoimmun 36:115-24
York, Nathan R; Mendoza, Jason P; Ortega, Sterling B et al. (2010) Immune regulatory CNS-reactive CD8+T cells in experimental autoimmune encephalomyelitis. J Autoimmun 35:33-44

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