Investigations of the pathway of procollagen biosynthesis and processing are being carried out with cell cultures. Both normal and naturally occurring mutant cell lines are being used in these studies. Attention is being focused on intracellular and extracellular procollagens, including the fibrous proteins found in the cell layer.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases (NIADDK)
Type
Research Project (R01)
Project #
5R01AM017220-13
Application #
3151044
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1976-09-01
Project End
1986-08-31
Budget Start
1985-09-01
Budget End
1986-08-31
Support Year
13
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Type
School of Medicine & Dentistry
DUNS #
City
Farmington
State
CT
Country
United States
Zip Code
Arumugham, R G; Hsieh, T C; Tanzer, M L et al. (1986) Structures of the asparagine-linked sugar chains of laminin. Biochim Biophys Acta 883:112-26