Abstract

The relationships between the motility of the digestive tract, intestinal transit, and intestinal absorption are being studied in animals and in healthy and diseased man. The influence of operations, hormones and electrical pacing on the motor patterns may suggest pathways for future therapies of identified disorders.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases (NIADDK)
Type
Research Project (R01)
Project #
5R01AM018278-11
Application #
3151128
Study Section
(GCN)
Project Start
1978-05-01
Project End
1986-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
11
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905

  Publications

Hoepfner, M T; Kelly, K A; Sarr, M G (1988) Pacing the canine ileostomy. Surgery 104:476-81
O'Connell, P R; Stryker, S J; Metcalf, A M et al. (1988) Anal canal pressure and motility after ileoanal anastomosis. Surg Gynecol Obstet 166:47-54
Bjorck, S; Ahlman, H; Dahlstrom, A et al. (1988) Serotonergic regulation of canine enteric motility (measured as electrical activity) and absorption: physiologic and morphologic evidence. Acta Physiol Scand 133:247-56
Morrison, P D; Kelly, K A (1987) Influence of a jejunal fistula on gastric emptying. Eur Surg Res 19:241-5
O'Connell, P R; Pemberton, J H; Brown, M L et al. (1987) Determinants of stool frequency after ileal pouch-anal anastomosis. Am J Surg 153:157-64
O'Connell, P R; Pemberton, J H; Kelly, K A (1987) Motor function of the ileal J pouch and its relation to clinical outcome after ileal pouch-anal anastomosis. World J Surg 11:735-41
Bjorck, S; Kelly, K A; Phillips, S F (1987) Mechanisms of enhanced canine enteric absorption with intestinal pacing. Am J Physiol 252:G548-53
O'Connell, P R; Kelly, K A (1987) Enteric transit and absorption after canine ileostomy. Effect of pacing. Arch Surg 122:1011-7
O'Connell, P R; Rankin, D R; Weiland, L H et al. (1986) Enteric bacteriology, absorption, morphology and emptying after ileal pouch-anal anastomosis. Br J Surg 73:909-14
O'Connell, P R; Kelly, K A; Brown, M L (1986) Scintigraphic assessment of neorectal motor function. J Nucl Med 27:460-4

Showing the most recent 10 out of 15 publications