The overall objective of the proposed research is to systematically assess the impact of psychosocial and stress dimensions upon outcome patterns of diabetic adolescents. Previous studies have indicated the importance of factors such as individual coping resources, life stress, and family environment in the adaptation of a patient to his or her chronic illness. Few studies have rigorously evaluated the influence of these variables upon favorable and unfavorable outcomes in Insulin-dependent Diabetes. In addition, none of the previous investigations have used longitudinal designs in studing the outcome. Our perspective is that to study those factors which underlie highly successful or problematic outcomes during adolescence, a multivariate research design is required. Our plan is to identify a cohort of newly-diagnosed diabetics, age 11-13 and a demographically matched control group of children being seen on an outpatient basis with an acute remitting illness. These patients and their families will be studied in terms of selected (through clinical and theoretical considerations) variables over the next four years. Variables to be studied include: 1) Familial coping strategies and interactions; 2) adolescent ego development and coping processes; 3) life stresses experienced by adolescents and their parents; 4) health locus of control; and 5) personality of adolescent and parents. In order to have our outcome measures most closely approximate the overall effect of a chronic disease, we have measures which are highly specific to diabetes (metabolic status and early long-term complications) and those which index other aspects of health status (self-esteem and psychosocial adjustment). Data analyses use multivariate statistical designs, with cross-sectional and longitudinal components.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases (NIADDK)
Type
Research Project (R01)
Project #
5R01AM027845-05
Application #
3151801
Study Section
Behavioral Medicine Study Section (BEM)
Project Start
1981-09-01
Project End
1986-11-30
Budget Start
1985-09-01
Budget End
1986-11-30
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Joslin Diabetes Center
Department
Type
DUNS #
071723084
City
Boston
State
MA
Country
United States
Zip Code
de Groot, M; Jacobson, A M; Samson, J A et al. (1999) Glycemic control and major depression in patients with type 1 and type 2 diabetes mellitus. J Psychosom Res 46:425-35
Cohen, S T; Welch, G; Jacobson, A M et al. (1997) The association of lifetime psychiatric illness and increased retinopathy in patients with type I diabetes mellitus. Psychosomatics 38:98-108
Jacobson, A M; de Groot, M; Samson, J A (1994) The evaluation of two measures of quality of life in patients with type I and type II diabetes. Diabetes Care 17:267-74
Jacobson, A M; Hauser, S T; Lavori, P et al. (1994) Family environment and glycemic control: a four-year prospective study of children and adolescents with insulin-dependent diabetes mellitus. Psychosom Med 56:401-9
Jacobson, A M; Hauser, S T; Lavori, P et al. (1990) Adherence among children and adolescents with insulin-dependent diabetes mellitus over a four-year longitudinal follow-up: I. The influence of patient coping and adjustment. J Pediatr Psychol 15:511-26
Hauser, S T; Jacobson, A M; Lavori, P et al. (1990) Adherence among children and adolescents with insulin-dependent diabetes mellitus over a four-year longitudinal follow-up: II. Immediate and long-term linkages with the family milieu. J Pediatr Psychol 15:527-42
Herskowitz, R D (1990) Outward bound, diabetes and motivation: experiential education in a wilderness setting. Diabet Med 7:633-8
Hauser, S T; Paul, E L; Jacobson, A M et al. (1988) How families cope with diabetes in adolescence. An approach and case analyses. Pediatrician 15:80-94
Wulsin, L R; Jacobson, A M; Rand, L I (1987) Psychosocial aspects of diabetic retinopathy. Diabetes Care 10:367-73
Jacobson, A M; Hauser, S T; Wolfsdorf, J I et al. (1987) Psychologic predictors of compliance in children with recent onset of diabetes mellitus. J Pediatr 110:805-11

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