Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
2R01AR020358-11
Application #
3155111
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1977-09-15
Project End
1987-06-30
Budget Start
1987-01-01
Budget End
1987-06-30
Support Year
11
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Vudattu, Nalini K; Strle, Klemen; Steere, Allen C et al. (2013) Dysregulation of CD4+CD25(high) T cells in the synovial fluid of patients with antibiotic-refractory Lyme arthritis. Arthritis Rheum 65:1643-53
Drouin, Elise E; Seward, Robert J; Strle, Klemen et al. (2013) A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease. Arthritis Rheum 65:186-96
Katchar, Kia; Drouin, Elise E; Steere, Allen C (2013) Natural killer cells and natural killer T cells in Lyme arthritis. Arthritis Res Ther 15:R183
Li, Xin; Strle, Klemen; Wang, Peng et al. (2013) Tick-specific borrelial antigens appear to be upregulated in American but not European patients with Lyme arthritis, a late manifestation of Lyme borreliosis. J Infect Dis 208:934-41
Strle, Klemen; Shin, Junghee J; Glickstein, Lisa J et al. (2012) Association of a Toll-like receptor 1 polymorphism with heightened Th1 inflammatory responses and antibiotic-refractory Lyme arthritis. Arthritis Rheum 64:1497-507
Seward, Robert J; Drouin, Elise E; Steere, Allen C et al. (2011) Peptides presented by HLA-DR molecules in synovia of patients with rheumatoid arthritis or antibiotic-refractory Lyme arthritis. Mol Cell Proteomics 10:M110.002477
Li, Xin; McHugh, Gail A; Damle, Nitin et al. (2011) Burden and viability of Borrelia burgdorferi in skin and joints of patients with erythema migrans or lyme arthritis. Arthritis Rheum 63:2238-47
Steere, Allen C; Drouin, Elise E; Glickstein, Lisa J (2011) Relationship between immunity to Borrelia burgdorferi outer-surface protein A (OspA) and Lyme arthritis. Clin Infect Dis 52 Suppl 3:s259-65
Strle, Klemen; Jones, Kathryn L; Drouin, Elise E et al. (2011) Borrelia burgdorferi RST1 (OspC type A) genotype is associated with greater inflammation and more severe Lyme disease. Am J Pathol 178:2726-39
Yakimchuk, Konstantin; Roura-Mir, Carme; Magalhaes, Kelly G et al. (2011) Borrelia burgdorferi infection regulates CD1 expression in human cells and tissues via IL1-?. Eur J Immunol 41:694-705

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