Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR028450-14
Application #
2078655
Study Section
Special Emphasis Panel (ZRG4-GMA-2 (01))
Project Start
1987-01-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Dermatology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Li, Qiaoli; Kingman, Joshua; van de Wetering, Koen et al. (2017) Abcc6 Knockout Rat Model Highlights the Role of Liver in PPi Homeostasis in Pseudoxanthoma Elasticum. J Invest Dermatol 137:1025-1032
Li, Qiaoli; Kingman, Joshua; Sundberg, John P et al. (2016) Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy. J Invest Dermatol 136:275-283
Li, Qiaoli; Kingman, Joshua; Uitto, Jouni (2015) Mineral content of the maternal diet influences ectopic mineralization in offspring of Abcc6(-/-) mice. Cell Cycle 14:3184-9
Jin, Liang; Jiang, Qiujie; Wu, Zhengsheng et al. (2015) Genetic heterogeneity of pseudoxanthoma elasticum: the Chinese signature profile of ABCC6 and ENPP1 mutations. J Invest Dermatol 135:1294-1302
Li, Qiaoli; Sundberg, John P; Levine, Michael A et al. (2015) The effects of bisphosphonates on ectopic soft tissue mineralization caused by mutations in the ABCC6 gene. Cell Cycle 14:1082-9
Li, Qiaoli; Chou, David W; Price, Thea P et al. (2014) Genetic modulation of nephrocalcinosis in mouse models of ectopic mineralization: the Abcc6(tm1Jfk) and Enpp1(asj) mutant mice. Lab Invest 94:623-32
Li, Qiaoli; Price, Thea P; Sundberg, John P et al. (2014) Juxta-articular joint-capsule mineralization in CD73 deficient mice: similarities to patients with NT5E mutations. Cell Cycle 13:2609-15
Li, Qiaoli; Guo, Haitao; Chou, David W et al. (2014) Mouse models for pseudoxanthoma elasticum: genetic and dietary modulation of the ectopic mineralization phenotypes. PLoS One 9:e89268
Li, Qiaoli; Pratt, C Herbert; Dionne, Louise A et al. (2014) Spontaneous asj-2J mutant mouse as a model for generalized arterial calcification of infancy: a large deletion/insertion mutation in the Enpp1 gene. PLoS One 9:e113542
Boraldi, Federica; Bartolomeo, Angelica; Li, Qiaoli et al. (2014) Changes in dermal fibroblasts from Abcc6(-/-) mice are present before and after the onset of ectopic tissue mineralization. J Invest Dermatol 134:1855-1861

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